[Perforated intestinal leiomyosarcoma].
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Biomedical subjects
J A Rodríguez-Montes
Publications and source records attributed to J A Rodríguez-Montes.
[Trophic activity of neurotensin in massive intestinal resection].
Regulatory peptides are among the main factors affecting the proliferative adaptive process of the small bowel; its mechanisms of action remains unknown. An 80% small bowel resection was done in Wistar rats (250-300 g) randomly assigned to two groups: control and neurotensin (300 mu/kg). Jejunal and ileal samples were taken on day 14 post-resection and histomorphometric (villous length) and proliferative (DNA content) measures were obtained. Results show an increase in villous length in the neurotensin group but no changes in DNA content were observed. We conclude that neurotensin increases intestinal mucosal growth after massive intestinal resection in the rat.
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[The effect of resection of the jejunum and ileum on intestinal mucosal trophism. An experimental study on the rat].
Intestinal resection leads to anatomo-physiological adaptive changes in the small bowel depending on its localization and extension. Two 50% resection models were done, jejunal resection (55 cm.) and ileal resection (55 cm.), in the attempt to determine the trophic response of the remnant bowel from jejunal and ileal samples. Significant increases were seen in mucosal villous length, jejunal values were greater than ileal and the greatest values were when the whole ileum was conserved. No significant changes were observed in DNA contents. These data suggest the importance of the ileal segment in the intestinal adaptive process, especially on the jejunal segment, as well as the apparent end of this response two weeks after resection.
Animals↗