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Biomedical subjects

J A Rosen

Publications and source records attributed to J A Rosen.

15 recordsLinked to original sources
PubMed1983

Observations on the efficacy of propranolol for the prophylaxis of migraine.

Among 1,036 patients treated for migraine headache between 1973 and 1980, 865 were given a daily maximum dose of 320 mg of propranolol, while 171 served as differently treated controls. At least one year of treatment was prescribed, at the end of which time 84% of the propranolol group reported sustained improvement compared with similar improvement in only 32% of controls (p less than 0.01). The success rate progressively increased during the entire year.

Adolescent↗
PubMed1979

Failure of chronic dorsal column stimulation in multiple sclerosis.

In view of the favorable claims of Cook and others, an open trial of chronic dorsal column stimulation was undertaken in 9 patients who had moderately advanced multiple sclerosis (MS) but were still ambulatory. No objective improvement was noted by either author during the postoperative observation period of 6 to 37 months; the occasional subjective improvement was ascribed to placebo effect. This procedure can no longer be recommended for MS patients.

Adult↗
PubMed1979

Prolonged azathioprine treatment of non-remitting multiple sclerosis.

Two groups of 85 and 42 ambulatory patients with moderately advanced non-remitting multiple sclerosis were treated for six to 14 and three to six years with daily azathioprine. Less than 10% of these patients became confined to a wheelchair. This far exceeds any possible result in a group of non-remitting multiple sclerosis patients not so treated.

Adult↗