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Biomedical subjects

J A Ruiperez Abizanda

Publications and source records attributed to J A Ruiperez Abizanda.

5 recordsLinked to original sources

Transdermal scopolamine as treatment of bradyarrhythmias.

Fifteen patients with different degrees of chronic bradyarrhythmias of supraventricular origin were studied with Holter monitoring before and during application of a transdermal patch of scopolamine. No changes were found in the mean or minimal heart rates, standard deviation of the RR interval, or the degree of bradyarrhythmia. It is concluded that transdermal scopolamine is not an adequate treatment of chronic symptomatic bradyarrhythmias.

Administration, Cutaneous↗

[Calculation of the mean pressure of the pulmonary artery and of the valve surface by ECG in mitral stenosis].

From a group of 50 patients affected by pure mitral stenosis with sinus rhythm, we have tried to obtain multiple correlation equations which enable in to calculate, in each particular case, the mean pressure of the pulmonary artery and mitral valvular area from purely electrocardiographic facts. In an additional group of 16 patients we have been able to verify the mentioned equations, placing all the calculated points within the presumed limits of tolerance. So it appears that the electrocardiographic calculation of these hemodynamic parameters is possible, with sufficient approximation for clinical requirements.

Blood Pressure Determination↗

[Comparative hemodynamic study of ventricular and sequential stimulation].

Cardiac catheterization was performed in 10 patients to compare the haemodynamic effects of ventricular stimulation and the sequential stimulation by measuring cardiac output and aortic pressure in both types of pacing. During sequential stimulation we had was an increase of 16.4% in cardiac output while there was increase in aortic and a decrease in pulmonary pressures. They improved significantly the haemodynamic parameters in our patients when compared to the ventricular stimulation.

Blood Pressure↗

[Long-term follow up of Doppler parameters of ventricular diastolic function after myocardial infarct].

Forty-two survivors of a first transmural, noncomplicated myocardial infarction underwent mitral flow pulsed-Doppler studies both at predischarge time and 1 year later, in order to assess the long-term evolution of diastolic parameters in the absence of reinfarction or revascularization procedures. Results showed a decrease of mean value of E wave peak velocity (59.6 +/- 14 cm/sec vs 46.8 +/- 13 cm/sec, p < 0.001). Mean value of A wave peak velocity remained stable (59.4 +/- 16 cm/sec vs 58.8 +/- 13 cm/sec, p = 0.86). The mean value of the E/A ratio showed a significant decrease during follow-up from an initial value > or = 1 to a final value < 1 (1.08 +/- 0.4 vs 0.82 +/- 0.2, p < 0.01). From the point of view of individual results, only 8 of 22 patients with an E/A ratio > or = 1 before discharge presented the same ratio value 1 year later, whereas only 1 patient with a E/A ratio < 1 before discharge presented a > 1 value of this ratio in the late study. It is concluded that during the first year of evolution after transmural, nonrevascularized, noncomplicated infarction, the left ventricle filling pattern displays a significant change from predischarge phase (mainly protodiastolic with predominant E wave) to late follow-up (mainly telediastolic with predominant A wave). Different hypotheses to explain these results are discussed.

Adult↗