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Biomedical subjects

J A Sorensen

Publications and source records attributed to J A Sorensen.

At least 19 recordsLinked to original sources
PubMed1996

Relative gap formation adjacent to ceramic inlays with combinations of resin cements and dentin bonding agents.

This study investigated the effect of combining dentin bonding agents (DBAs) with various resin cements on contraction gap formation at the cavity floor of resin-cemented ceramic inlays. Cylindrical dentin cavities were pretreated with one of five DBAs before luting of ceramic inlays with one of four dualcuring resin cements. Measurements of cross sections showed that mean gap widths were reduced from 46% to 93% compared with control specimens prepared without a DBA. The extent of the gap reduction was dependent on the type of bonding agent and resin cement. Although none of the resin cement-dentin bonding agent combinations tested were able to completely eliminate development of interfacial contraction gaps, some combinations produced considerable reductions in gap size.

Cementation↗
PubMed1996

Relative gap formation of resin-cemented ceramic inlays and dentin bonding agents.

The effect of dentin bonding agents (DBAs) on contraction gap formation at the cavity floor of resin-cemented ceramic inlays was investigated. Cylindrical dentin cavities were pretreated with one of 12 DBAs before luting of ceramic inlays with a dual-curing resin cement. Measurements of cross sections revealed that mean gap widths were reduced between 21% and 80% compared with control specimens prepared without a DBA. The extent of the gap reduction depended on the type of bonding agent. None of the dentin bonding agents tested were able to completely eliminate development of interfacial gaps.

Cementation↗
PubMed1996

A clinical trial of all-ceramic crown restorations: status, fall 1995.

Although porcelain-fused-to-metal (PFM) restorations are the most widely used full-coverage crown restoration systems, their inherent properties make the achievement of natural aesthetic restorations an elusive task. In contrast, the all-ceramic system (IPS Empress, Ivoclar North America, Amherst, NY) offers excellent translucency and vitality, without the opacity associated with PFM restorations. Its vitality is further enhanced by an adhesive resin cementation method that conducts the color of the underlying tooth structure. This article reports the status of a 5-year investigation, initiated in 1992, of the clinical performance of the IPS Empress all-ceramic system and the resin cementation system used with it.

Adolescent↗
PubMed1995

Ceramic inlay movement during polymerization of resin luting cements.

In cavities with no support for inlays, polymerization contraction of the resin cement may move the ceramic inlay axially. The purpose of this study was to determine the velocity and extent of such movement. Cylindrical ceramic inlays were placed in dentin cavities filled with one of four commercially available resin composite cements. An initial standardized 200-microns-thick cement film was created. The movement of the ceramic inlay during polymerization of one of the resin cements was measured by a dial gauge. The velocity of the inlay movement decreased exponentially with time and with a velocity constant of 0.09 min-1. The majority of the movement occurred within the first 12 min after photopolymerization and probably continued for several days, reaching an estimated value of 5.8 microns. After 1-2 d of water storage, 1-2-microns contraction gaps at the cavity floors were observed microscopically for every cement used. It is concluded that in cavities without support for the inlay, about 2/3 of the resin cement contraction results in movement of the inlay and about 1/3 results in formation of gaps at the cavity floors.

Analysis of Variance↗
PubMed1995

Interfacial gaps of resin cemented ceramic inlays.

A method was developed for measuring presence, location and extent of interfacial contraction gaps of resin-cemented ceramic inlays in dentin cavities. Cylindrical ceramic inlays were cemented using one of 12 commercially available resin composite cements to make a film thickness of 200-microns. Cross-sections revealed absence of marginal gaps but contraction gaps occurred at all dentin-cement interfaces at the cavity floors and ranged from 1.6 to 7.1 microns. This was equivalent to 0.8-3.5% of the cement film thickness and was 3-10 times greater than the wall-to-wall contraction in percent observed when resin composites are used as filling materials in 3-5 mm butt-joint dentin cavities. The results support the theory that contraction gaps developing adjacent to thin films of resin cements reach a size equivalent to the cement film thickness multiplied by the volumetric polymerization shrinkage of the cement.

Adhesiveness↗
PubMed1995

Failure of all-ceramic fixed partial dentures in vitro and in vivo: analysis and modeling.

Hertzian cone cracks visible at the loading site of 20 all-ceramic fixed partial dentures (FPDs), tested in vitro, led to the hypotheses that failure was due to the propagation of localized contact damage crack systems (Hertzian stress state) and that such damage was an unlikely clinical failure mode. Fractographic analysis of the 20 laboratory-failed and nine clinically-failed all-ceramic FPDs allowed for definitive testing of these hypotheses and a comparison between in vitro and in vivo failure behavior. In all cases, failure occurred in the FPD connectors (none from contact damage), with approximately 70 to 78% originating from the interface between the core and veneer ceramics. The coincidence between failure origins provides strong evidence that the in vitro test modeled aspects of structural behavior having clinical importance. The fractographic observations, coupled with the in vitro failure load data, furnished very specific boundary conditions which were applied to constrain mathematical models of FPD connector failure. Finite element analysis (FEA) of the laboratory FPDs found that maximum principal tensile stresses would occur at locations consistent with the fractographic observations only if: (1) there were appropriate elastic moduli differences between the ceramics; and (2) a small amount of abutment rotation was allowed. Weibull failure probability (Pf) calculations, incorporating FEA stress profiles, very closely replicated the laboratory failure distribution only when: (1) the veneer ceramic was much weaker than the core ceramic; and (2) the Weibull modulus of the core-veneer interface was much lower than that for the free veneer surface (i.e., the interface is of lower quality with regard to defects).(ABSTRACT TRUNCATED AT 250 WORDS)

Ceramics↗
PubMed1994

Experimental localization of intestinal uptake sites for metals (Cd, Hg, Zn, Se) in vivo in mice.

The intestinal uptake process consists of two separable steps: transport over the luminal membrane into epithelial cytoplasm and transport over the basolateral membrane into serosal fluid. A compound's residence time in mucosal epithelial cytoplasm depends on rates of the two transport processes and, if the rate of the second step is low, on the rate of mucosal sloughing. Using gamma-emitting metal isotopes, in vivo labeling profiles of the intestinal tract were obtained from mice eating their normal diet. The results pertain to processes in the functioning, undisturbed intestinal tract. Single-dose chase experiments indicated that intestinal uptake processes were in fact studied. The labeling profiles varied considerably for different metals. Thus, Cd++ was absorbed mainly in duodenum and early jejunum, while Zn++ was taken up in jejunum and ileum. The uptake profile of Hg++ indicated most rapid uptake in proximal jejunum. Selenomethionine labeled the entire intestinal tract, most rapidly the duodenum, the following intestinal segments were labeled with falling rate. This experimental method is rapid and simple. Further studies aim at developing a quantitative model suited for studying interactions between essential and toxic metals at the level of intestinal metabolism.

Animals↗
PubMed1993

Identification of the gastrointestinal absorption site for cadmium chloride in vivo.

Most models for the study of the mechanism of intestinal absorption of Cadmium (Cd) have been using intestinal tissue in vitro or in situ. The in vivo experiments reported in this article were performed in an attempt to localize the site for gastrointestinal absorption of cadmium chloride during natural physiological conditions by oral exposure of mice to 109Cd-labelled CdCl2. Independent of exposure via drinking water or oral administration of a single dose, Cd was primarily deposited in the most proximal duodenum. Thus the present study as well as others indicate that absorption takes place in the proximal part of the intestine. Absorbed Cd is initially transported to the liver and deposited before being redistributed and accumulated in the kidneys. In this experimental model, dietary tetraethylthiuram disulfide exposure was shown to change the intestinal labelling profile and increase the whole-body retention as well as the intestinal deposition of Cd.

Administration, Oral↗
PubMed1992

Marginal fidelity and microleakage of porcelain veneers made by two techniques.

This study evaluated the marginal fidelity and microleakage of porcelain veneers made with the platinum foil and refractory die techniques. Maxillary incisors, matched for size and amount of enamel, were prepared with 0.5 mm uniform intraenamel reduction. The indirectly made veneers were etched, treated with silane, and luted with a composite resin, and the margins were finished and polished. The restored teeth were stored in 37 degrees C water, thermocycled 1000 times, stained with silver nitrate, embedded, sectioned buccolingually and mesiodistally, and measured at x250 magnification. The platinum foil veneers had significantly better vertical marginal fidelity but significantly more overcontouring than had the refractory die veneers. Universal microleakage at the tooth-composite resin interface and negligible microleakage at the porcelain-composite resin interface were observed. No relationship was found between the amount of vertical marginal opening and the amount of microleakage.

Acid Etching, Dental↗
PubMed1992

Microleakage of new crown and fixed partial denture luting agents.

This study measured the in vitro microleakage of conventional and new FPD luting agents. Standardized preparations were made on 42 freshly extracted premolars. Facial and lingual chamfer margins were placed in enamel, mesial and distal in dentin and cementum, and castings were made in Rexillium III alloy and were then cemented with a standardized technique. Six groups of seven samples were tested, (1) polycarboxylate, (2) zinc phosphate, (3) glass ionomer, (4) Den-Mat Thin Film cement, (5) Panavia Ex, and (6) Den-Mat Thin Film cement with Tenure. The ranking of groups for stain ingress was from the greatest (1) to the least (6). A one-way analysis of variance and Tukey-Student range analysis revealed significantly similar groups, p less than 0.05:(1,2,3,4) (5,6).

Adhesives↗
PubMed1992

Marginal fidelity of four methods of swaged metal matrix crown fabrication.

The swaged metal matrix provides a method for rapidly making a metal substructure for ceramic crowns. This study determined the vertical and horizontal marginal fidelity of swaged metal substrate crowns made with four methods. No significant difference in vertical or horizontal marginal fidelity was found for metal margin crowns formed with either a plastic spacer or a paint-on die spacer. The vertical marginal fidelity was significantly better in crowns made with a metal margin (37 microns) than in crowns made with a porcelain facial margin (62 microns), and the latter were significantly better than crowns made with a 360-degrees porcelain margin (86 microns). Crowns made with all four methods were overcontoured by 46 to 82 microns. The 360-degrees porcelain margin was technically more difficult and time-consuming to make.

Analysis of Variance↗
PubMed1991

Gingival enhancement in fixed prosthodontics. Part I: Clinical findings.

This study assessed the efficacy of a 0.12% chlorhexidine gluconate (CHX) rinse on the enhancement and maintenance of gingival health in patients receiving fixed prosthodontic treatment. Thirty patient participants in this examiner blind study were randomly assigned into two groups, one control and another group using CHX 15 ml b.i.d. in addition to normal oral hygiene. The medication was used for 2 weeks prior to crown preparation, 3 weeks during provisional crown placement, and 2 weeks after definitive crown cementation. Plaque and gingivitis indices were measured initially and at the three aforementioned points during the 7-week period. The plaque index for the control group decreased by 0.26 units; CHX decreased by 0.63 units at 7 weeks. The gingival index of the control group decreased by 0.37 units; CHX decreased by 0.87 units. Adjunctive use of chlorhexidine with fixed prosthodontic procedures significantly reduced plaque levels and significantly improved gingival health compared with the control patients. Fixed prosthodontic procedures alone decreased plaque levels and increased gingival health.

Adult↗
PubMed1991

Gingival enhancement in fixed prosthodontics. Part II: Microbiologic findings.

This study assessed the changes of the subgingival/marginal microflora during fixed prosthodontic procedures and evaluated the effect of adjunctive rinsing with 0.12% chlorhexidine on the subgingival/marginal microflora during fixed prosthodontic treatment. Thirty patients scheduled for fixed prosthodontics were randomly assigned to either rinsing with 15 ml of tap water b.i.d. (control) or rinsing with 15 ml of 0.12% chlorhexidine gluconate b.i.d. (experimental). Subgingival and marginal plaque was analyzed at baseline, before crown preparation (2 weeks), before crown cementation (5 weeks), and 2 weeks after cementation (7 weeks). The fixed prosthodontic procedures alone altered the subgingival and marginal microbiota toward a more health-associated flora. Adjunctive rinsing twice daily with 0.12% chlorhexidine had a significantly greater effect in reducing putative periodontal pathogens compared with the control regimen. This medication was a useful adjunct to regular oral hygiene during fixed prosthodontic procedures by permitting the establishment and maintenance of a microflora compatible with periodontal health.

Adult↗
PubMed1991

Gingival enhancement in fixed prosthodontics. Part III: Anamnestic findings.

This study obtained anamnestic data from a questionnaire given at the conclusion of a 7-week chlorhexidine gingival enhancement study regarding patients' oral hygiene practices, perception of change in gingival health, and side effects. In the patient population using the 7-week chlorhexidine treatment regimen, most patients noticed an improvement in gingival health, were willing to continue usage after the study, and would recommend the rinse to others. Of the patients who reported side effects, taste alteration was more objectionable than staining. The patients' observed gingival health benefits were more important than the patients' perception of the side effects such as staining and taste alteration.

Adult↗
PubMed1991

Porcelain-composite interface microleakage with various porcelain surface treatments.

This study evaluated the effects of various porcelain surface treatments on the microleakage of the porcelain-composite interface. The experimental model isolated and evaluated only the porcelain-composite interface without the presence of a bond to tooth structure. Four types of porcelain were fired into circular porcelain tabs 1.0 mm thick by 8.5 mm in diameter. The groups of porcelain were divided into subgroups for treatment with hydrofluoric acid-etching and silane. A jig standardizing composite thickness to 0.2 mm was used to photopolymerize composite to porcelain. The margins were finished and polished with burs and disks. Samples were stored in 37 degrees C water thermocycled 1000X, placed in AgNO3 solution, embedded in epoxy, and cross-sectioned every 90 degrees for measurement of stain penetration at the composite-porcelain interface. Occasional crazing of porcelain from composite polymerization shrinkage was observed. Porcelain surface treatment significantly increased the specimens' ability to withstand water storage and thermal-cycling procedures. Porcelain surface treatment with silane alone did not reduce microleakage, but, in combination with etching, reduced microleakage significantly.

Acid Etching, Dental↗
PubMed1990

Effect of post adaptation on fracture resistance of endodontically treated teeth.

This study determined the effect of different post designs and varying amounts of post-to-canal adaptation on the fracture resistance of endodontically treated teeth. Forty freshly extracted maxillary central incisors were endodontically treated. Groups of 10 teeth were prepared according to four experimental designs. Cast post and cores and crowns were waxed, cast, and luted with zinc phosphate cement on a static loading device. The teeth were embedded in acrylic resin and the crowns were loaded on a universal testing machine at 130 degrees to the long axis of the tooth until failure. Maximum adaptation of the residual root structure with a tapered post significantly increases the fracture resistance of endodontically treated teeth, but upon failure renders the tooth nonrestorable. Tapered posts resulted in fractures that were directed more apically and lingually. Parallel-sided posts had a lower frequency of fracture upon failure, involving less tooth structure. Parallel-sided posts surrounded by large amounts of cement had no significant effect on failure loads.

Analysis of Variance↗
PubMed1990

Ferrule design and fracture resistance of endodontically treated teeth.

This study evaluated the fracture resistance of pulpless teeth with various ferrule designs and amounts of coronal tooth structure. One millimeter of coronal tooth structure above the crown margin substantially increased the fracture resistance of endodontically treated teeth, whereas a contrabevel at either the tooth-core junction or the crown margin was ineffective. The thickness of axial tooth structure at the crown margin did not appreciably improve resistance to fracture.

Analysis of Variance↗