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Biomedical subjects

J A Svirsky

Publications and source records attributed to J A Svirsky.

12 recordsLinked to original sources
PubMed1992

The prevalence of oral lesions in smokeless tobacco users and an evaluation of risk factors.

BACKGROUND: The widespread use of smokeless tobacco (ST) has prompted concern in regard to the development of oral lesions in long-term users. METHODS: For inclusion in the current study, a subject must have used an ST product, either snuff or chewing tobacco, for at least 6 months. The subjects were recruited by advertising, and none was referred for the evaluation of an oral lesion. The following were performed on all subjects: assessment of exposure to ST, cigarettes, and alcohol; examination of the oral cavity; a biopsy, if an oral lesion was found; and analysis of a blood sample for beta-carotene. The dietary intake of most of the subjects was analyzed. RESULTS: Of the 347 ST users, all of whom were white male subjects, 45 (13.0%) had an oral lesion. Thirty-five of the lesions were hyperkeratosis and 10 were epithelial dysplasia. CONCLUSIONS: Snuff exposure was associated significantly with the presence of an oral lesion (P < 0.0001). A decreased vitamin C intake also was found among the ST users with oral lesions (P < 0.01). The ST users with epithelial dysplasia, as compared with those with hyperkeratotic lesions, were slightly older, had a lower intake of vitamin C (P < 0.05), and were more likely to have used chewing tobacco than snuff.

Adult↗
PubMed1989

Dental management of patients after liver transplantation.

Liver transplantation over the past 10 years has become a nonexperimental therapy for patients with end-stage liver disease and offers hope to many for whom no treatment was previously available. As more patients undergo liver transplantation and survival rates continue to improve, the dental profession must adopt a protocol for dealing with these patients. With this in mind, a protocol for dental management of the patient who has had a liver transplant is presented. Two cases are presented to illustrate the importance of dental intervention.

Adult↗
PubMed1989

Rapidly enlarging gingival mass.

A case of small cell carcinoma metastatic to the mandible has been detailed. The lesion involved both hard and soft tissues and it was impossible to determine the site to which it first spread. Because of the histological similarity to the primary lung lesion and evidence of metastatic spread to other body organs, this lesion was considered to be metastatic rather than a primary tumor. The importance of accurate diagnosis was discussed, and treatment options were presented.

Carcinoma, Small Cell↗
PubMed1989

Intraosseous and extraosseous calcifying odontogenic cyst (Gorlin cyst).

This retrospective study of 15 central and five peripheral calcifying odontogenic cysts (COCs) was undertaken to compare the characteristics of these two lesions. The data reveal that the central COCs were more common than peripheral lesions by a 3:1 ratio and that they were usually diagnosed in the second decade of life, whereas the peripheral ones were usually noted after the age of 50. Seven of the 15 central COCs (47%) were associated with odontomas, and three (20%) with dentigerous cysts. Conservative enucleation or excision was the treatment of choice.

Adolescent↗
PubMed1989

Slow-growing, ulcerated mass of the left posterior hard palate.

The importance of a thorough oral and paraoral examination of all patients, with appropriate follow-up of abnormalities, cannot be overstated. The prognosis of any malignant lesion is improved if diagnosis and treatment are rendered early. This patient had an obvious lesion of the hard palate, 4 1/2 years before definitive diagnosis. When the lesion was first noted, prompt diagnostic evaluation may have discovered the malignant process. The lengthy delay in appropriate treatment for this patient has resulted in a potentially tragic outcome.

Aged↗
PubMed1977

Solitary intraoral keratoacanthoma.

A case of keratoacanthoma of the maxillary gingiva in a 12-year-old white boy has been presented. This is only the fourth case of solitary intraoral keratoacanthoma reported in the English-language literature. A review of the literature on solitary and multiple mucosal keratoacanthomas and the incidence of ectopic sebaceous glands has been included. In all mucous membrane locations where keratoacanthomas have arisen, there have been other reported cases of ectopic sebaceous glands in these areas. These findings have led us to consider that intraoral and perhaps all mucous membrane keratoacanthomas arise i, sebaceous glands or their ducts, whether they be normal in their location, as in the buccal mucosa, or ectopic.

Child↗
PubMedDate not supplied

Smokeless tobacco.

Explore the source record for details and available documents.

Humans↗
PubMedDate not supplied

Chlorhexidine as an oral hygiene adjunct for cyclosporine-induced gingival hyperplasia.

Recent advances in surgical technique and chemotherapeutic procedures have greatly increased the survival rates of organ transplantation patients. Of dental importance is the widespread use of the immunosuppressive agent cyclosporine in this special-patient population, a drug that has the potential to cause severe gingival hyperplasia as a side effect. A case is presented illustrating the use of the plaque-inhibitor chlorhexidine as a therapeutic adjunct in possibly arresting this gingival condition.

Child, Preschool↗