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Biomedical subjects

J A Vento

Publications and source records attributed to J A Vento.

15 recordsLinked to original sources
PubMed1999

Massive and widely distributed splenosis.

A 45-year-old man, seropositive for hepatitis C, was examined because his liver was palpable well below the costal margin. A CT examination revealed multiple nodules within the liver and also several sites of ectopic tissue. The patient had a splenectomy 25 years before. A radiocolloid study showed uptake, consistent with splenosis, in the thorax, abdomen, pelvis, and possibly the left arm. The magnitude of the ectopic tissue, and its multiple locations, indicated the ability of splenic cells to grow in a variety of body sites.

Humans↗
PubMed1999

Aortic calcification contributing to bone densitometry measurement.

A 75-yr-old glucocorticoid-dependent asthmatic male had a bone mineral density study to assess possible osteoporosis prior to initiating therapy. A radiograph of the lumbar spine revealed an asymmetrical compression of the second lumbar vertebra, marked scoliosis, vertebral osteopenia, and a highly calcified abdominal aorta. Bone mineral density (dual X-ray absolptiometry [DXA]) revealed low bone mass in L2-L4 and a markedly abnonrnal pattern, with a linear central density representing a calcified aorta. Posterior-anterior measurements of the midlumbar region with and without the overlying aorta indicated that the calcified vessel contributed up to 33% of the measured density. This was a far higher contribution than reported in other studies. Lateral DXA measurements of the L2 vertebra and the overlying aorta were performed to validate this finding. The density of the L2 vertebra was 0.215 g/cm(2), and that of the overlying calcified aorta was 0. 210 g/cm(2). This case suggests that aortic calcifications may contribute sign)ficantly to overall lumbar bone density and, unless recognized, can inadvertently lead to misclassification of osteoporosis.

Absorptiometry, Photon↗
PubMed1986

Multifocal osteogenic sarcoma in the seventh decade.

A 64-year-old man with right knee pain had uptake of Tc-99m MDP in the area as well as in the greater trochanter. Both sites were shown to contain osteogenic sarcoma. There was resection of the bone. Eight months later, radiogallium uptake was avid in the nearby soft tissue, indicating tumor spread.

Femoral Neoplasms↗
PubMed1986

Bilateral "simultaneous" femoral neck fractures following minimal stress.

Following jogging, a 53-year-old man experienced bilateral hip discomfort. Two weeks later, after stepping backward suddenly, he had severe pain in the right hip. Radiographs showed a displaced fracture of the right femoral head; this was pinned. Bone imaging revealed intense uptake in the other femoral head as well. This also was believed to be fractured, and therefore was repaired. During the two operations, no pathological cause of the bilateral femoral neck fractures was noted. The literature on simultaneous bilateral femoral neck fractures, without underlying bone disease, was reviewed.

Athletic Injuries↗
PubMed1986

False-positive spleen imaging. Splenic cleft and accessory spleen.

Following trauma, a 35-year-old man had a falling hematocrit. Radiocolloid imaging showed a superior pole splenic defect with a bilobed appearance (suggesting nearly complete trans-section). There was a small quantity of function below the main portion of the spleen. At surgery, the spleen was noted to have marked lobulation (perhaps congenital) to account for the upper pole defect and trans-splenic appearance of a tear. A small accessory spleen was present below the main organ, mimicking the appearance of organ disruption. Cases of false-positive radiocolloid images, suggesting trauma, are rare but do occur.

Adult↗
PubMed1986

Graves' disease. Initial presentation with exophthalmos and solitary hot nodule.

A 52-year-old man presented with left exophthalmos. A thyroid scan showed a right lobe hot nodule with suppression of the remainder of the gland. Thyroid function tests were normal. In less than two years, the patient had worsening of the exophthalmos. Thyroid indices then revealed hyperthyroidism and the thyroid image had markedly altered (with evidence of diffuse function). This change, initially showing a hot nodule and then diffuse thyroid overactivity, has been reported previously in three cases (all women). Characteristics of the disorder in these four individuals were reviewed. It is possible that the patients had two distinct diseases, separated temporally.

Graves Disease↗