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J A Verheul

Publications and source records attributed to J A Verheul.

4 recordsLinked to original sources

The congenital bicuspid aortic valve with post-inflammatory disease--a neglected pathological diagnosis of clinical relevance.

It is unusual to find surgically excised congenital bicuspid aortic valves with post-inflammatory disease. We have analysed retrospectively all surgically excised aortic valves over a 6-year period for this particular diseased state in relation to relevant clinical data. There were 181 congenital bicuspid aortic valves, and the characteristic gross pathology of the tricuspid aortic valve with post-inflammatory disease served as reference. Twelve of the 181 congenital bicuspid aortic valves were identified as post-inflammatory (6.6%); one with clinically established rheumatic disease. The mean age at operation of these 12 patients was significantly lower compared to 'other' aortic valves. The study indicates that post-inflammatory involvement of a congenital bicuspid aortic valve can be identified, which is of clinical relevance since these patients have a significantly younger age at operation.

Adult↗

[Balloon valvuloplasty of the aortic valve: short-term and medium-term results in 50 patients].

Fifty patients with severe symptomatic aortic stenosis underwent a balloon valvuloplasty of the aortic valve with acceptable initial haemodynamic results. Follow-up at one month showed clinical improvement in 66% of the patients. Long-term follow-up (clinical, Doppler echocardiography and repeat cardiac catheterization) was disappointing. The intervention-free rates at one and two years were 44% and 26%, respectively. Aortic balloon valvuloplasty should be limited to patients with a severe aortic stenosis and short life expectancy because of non-cardiac disease and to patients with severely depressed left ventricular function as a bridge to valve replacement.

Adult↗