Biomedical subjects
Publications and source records attributed to J A Woltjen.
Lymphangiomas are benign tumors most commonly found in the neck, axilla and skin. Occasionally they may occur in the gastrointestinal tract, most in the small intestine or mesentary. Lymphangioma of the colon is rare. Many of the reported cases, however, have manifested similar radiographic features. This case exemplifies the characteristic radiographic and colonoscopic features which may suggest the diagnosis.
Recent evidence has suggested that peripheral blood suppressor cell populations can modulate immune responsiveness. Absence of suppressor cell activity has been noted in diseases of presumed autoimmune basis. We determined inducible suppressor cell activity in patients with primary biliary cirrhosis (PBC) as compared to age and sex-matched controls. There was a significant loss of suppressor cell activity for mitogen response in patients with PBC (-4.5 +/- 8.0%) versus controls (43.7 +/- 7.8%). No correlation of this loss to clinical parameters was observed. This study suggests PBC patients lack inducible suppressor cell activity provide partial explanation for the perpetuation of this disease.
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