Biomedical subjects
Publications and source records attributed to J Abjean.
Cyclosporine A selectively inhibits T cell function with minimal effect on humoral immunity. It is largely used with success in kidney transplants. A clinical case of gingival overgrowth secondary to cyclosporine therapy in a 11 year old male who received a kidney transplant is reported. Surgical excision of the excess tissue, light and electron microscopic study are accomplished.
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The purpose of the present work was to study the response of human periodontium to hydroxyapatite biomaterial particles (180-200 microns). The biomaterial was implanted in two infra-osseous periodontal defects (two patients) after clearing of the granulation tissue. At two months post-surgery, biopsies were studied using light and electron microscopy. No sign of inflammation was observed, the biomaterial aggregates were surrounded either by typical fibroblasts or larger phagocytotic cells with phagocytosis vesicles containing biomaterial crystals. These intracellular crystals were noticeably smaller than the non-phagocytized ones. Some of the phagocytized crystals showed morphological signs of intracellular dissolution. The spaces between the crystals constitutive of the aggregates were filled with organic substance containing collagen fibers.
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Since the use of cyclosporine A therapy in kidney, cardiac hepatitis livers pancrease transplants, the oral surgeon have seen gingival overgrowth under this immunosuppressive drug. In this article the authors reports 2 cases and accomplishes light and electron microscopic study. Gingivectomy is exposed.
The lateral condylar movement can be observed through cat scan images. A clinical method based on the muscular disconnection can be done after recording the physiologic arc of closure. The incisal jig and the relined occlusal basis are used to transfer the immediate side shift, the Benett movement the lateral progressive movement and the condylar inclination on a full adjustable DENAR D5A articulator.
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