Biomedical subjects
Publications and source records attributed to J Abreu González.
Hepatic cirrhosis secondary to deficit of alpha-1 antitrypsin is an entity rarely observed among the adult population. We describe the clinical and histological characteristics of a patient with PiZZ phenotype, affected by an hepatic cirrhosis of this etiology, as well as the analytical and phenotypical study of his close relatives, all of which presented a type-Z mutation.
Three patients, one adult, one adolescent and one child, with previous history of asthma difficult to treat and frequent acute crisis, were hospitalized with clinical signs of Life Threatening Asthma (LTA) refractory to intensive treatment, including intubation and mechanical ventilation, being treated with and inhaled anesthetic: Isoflurane. All patients responded satisfactorily to such treatment at a concentration varying from 0.5 to 1.5% and none of them suffered adverse reactions to the medication. The immediate therapeutic effect and the absence of intensive care are factors that indicate the use of Isoflurane.
Spontaneous pneumothorax can be a complication of several pulmonary diseases, such as pulmonary emphysema, chronic bronchitis and interstitial pulmonary disease. Nevertheless, it is a rare complication of any pneumonia, there is no description of necrosis or abscess caused by Pneumocystis Carinii pneumonia. We present a case of spontaneous pneumothorax (which was not resolved), being a reason for admission, of a patient with AIDS who developed Pneumocystis Carinii pneumonia during the stay in hospital. We think that spontaneous pneumothorax can register bad evolution in patients with AIDS and pulmonary symptoms.
Relapsing polychondritis is a disease of unknown etiology whose main characteristic is the chronic inflammation and destruction of the different cartilaginous structures of the body. A rare case is presented, the rareness being the fact that ear cartilage was not affected and that the destructive arthropathy was similar to that produced by rheumatoid arthritis.
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