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J Aguilar Ruiz

Publications and source records attributed to J Aguilar Ruiz.

16 recordsLinked to original sources
PubMed2002

[Parainfluenza virus type 4 infections].

OBJECTIVE: To describe the clinical and epidemiological characteristics of parainfluenza virus type 4 infections in pediatric patients. METHODS: Inpatients and outpatients with lower respiratory tract infections were studied. Recorded data were age, sex, clinical diagnosis, temperature, oxygen saturation, chest radiograph and length of hospital stay. Nasopharyngeal aspirates were studied through indirect immunofluorescence, tissue culture and a new multiplex reverse-transcriptase polymerase chain reaction (RT-PCR) able to identify the four types of human parainfluenza virus in the same reaction. RESULTS: Two hundred thirty specimens from 191 patients were analyzed. Parainfluenza viruses were diagnosed in 35.1 %: 37.3 % type 1, 10.4 % type 2, 38.9 % type 3 and 13.4 % type 4. RNA from parainfluenza virus type 4 was amplified in 10 aspirates from nine patients. Of these, all except one were aged less than two years (range: 26 days to 23 months). The clinical diagnosis was bronchiolitis or wheezing associated with lower respiratory tract infection. Six patients required admission, with a mean oxygen saturation of 89.5 % and a mean length of hospital stay of 7.6 days. DISCUSSION: This is the first description of the characteristics of parainfluenza virus type 4 in Spain. Infections associated with this virus are not as mild as previously thought. Application of a multiplex RT-PCR allows identification of respiratory infections due to parainfluenza virus type 4 that would otherwise be underdiagnosed.

Child↗
PubMed2001

[Viral infection of the lower respiratory tract in hospitalized infants: etiology, clinical features and risk factors].

OBJECTIVES: The aim of this study was to assess the clinical and virological characteristics of lower respiratory tract (LRT) infection in hospitalized infants in Spain and to identify clinical, radiological or laboratory parameters that could, on admission, be associated with a more severe clinical course. PATIENTS AND METHODS: A prospective study of infants less than 24 months old hospitalized for LRT infection during six consecutive seasons was performed. RESULTS: A total of 617 infants were included in the study. Diagnosis was bronchiolitis in 64 %, wheezy bronchitis in 24.6 %, laryngitis in 4.4 % and pneumonia in 6.8 %. The mean age was 269 188 days, the male/female ratio was 1:6 and the mean hospital stay was 6.6 3.5 days. At least one viral agent was identified in 55.6 % of the episodes, of which 83.6 % were due to respiratory syncytial virus (RSV). Other less frequently identified viruses were parainfluenza in 7 %, adenovirus in 4.3 % and influenza in 4 %. Coinfection was identified in 6.2 % of RSV-positive infants. These infants were younger (p < 0.005), had higher respiratory distress assessment instrument (RDAI) scores and longer hospital stay than infants in the other etiologic groups. Chest radiographs were performed in 94.3 % of the infants and 39.5 % showed infiltrate or atelectasis. This radiological alteration was significantly associated with a fever of more than 38.5 C and reactive C protein concentrations of more than 30 mg/L (p < 0.001 and p < 0.002), but not with higher RDAI score, SaO2 equal to or less than 87 %, or longer hospital stay. In the crude analysis, hospitalization for more than 5 days was associated with lower age (p < 0.01), a mean RDAI score of more than 6 (p < 0.003), SaO2 equal to or less than 87 % (p < 0.01) and RSV infection (p < 0.001). However, in the multivariate analysis only SaO2 equal to or less than 87 % and RSV infection were significantly associated with prolonged hospitalization. CONCLUSION: The most common lower respiratory tract infections in hospitalized infants in Spain are the various types of RSV-positive bronchiolitis, which have a clinical pattern similar to that described in other countries. Hypoxia on admission and RSV infection are the most important risk factors for prolonged hospitalization.

Female↗
PubMed1980

A crystallographic study of prostatic calculi.

We analyzed 70 prostatic calculi using crystallographic methods and determined the individual composition of the layers, structures and ultrastructures, thus, obtaining a more precise classification of these calculi.

Apatites↗
PubMedDate not supplied

[Densitometric study of staghorn lithiasis using computerized tomography].

Fifty staghorn calculi that had been removed surgically and previously analyzed for stone composition and structure were studied by tomodensitometry. The analysis consisted of measurements in absolute units and histographic configuration of x-ray attenuation-absorption of the lithiasic material. The reconstructed images were evaluated and the areas of interest were defined. Each section and area had the following universal elements: number of pixels studied and values for mean attenuation expressed as Hounsfield units (HU). In this manner, tomodensitometric mapping of the calculi could be performed. We underscore the usefulness of this procedure in investigation and the possibility of extrapolating the results to in vivo studies of calculi composition so that we can reliably predict the results attainable with treatment modalities such as ESWL or percutaneous surgery. Little has been published on this subject. To our knowledge, this is the first in Spain.

Densitometry↗
PubMedDate not supplied

[Structure of secondary or exogenous prostatic calculi].

Out of a series of 70 prostatic stones, we found 8 considered to be "secondary" or "exogenous" (i.e. originated inside the acinis, following the initial crystallization of the components of the orine introduced into the acini) which underwent crystallographic analysis, using basically the "fine plate" to determine their structure. There were found to be two types of stones: one kin essentially uric (5 in all) and others essentially oxalic (3). We observed that these may be formed by pure substances as in the case of two uric stones but generally the nucleus is made up of uric or oxalic components with a tendency in the periphery to form concentric layers of apatite or whitlockite, similar to those observed in primary or endogenous prostatic stones, accompanied by other oxalic or uric components or not. We found that both the uric acid (anhydrous) as well as the oxalates may adopt the same strucutre presented by the urinary stones (renal, vesical) but the anhydrous, uric acid may also present in the nucleus of a stone, an association of 3 structures (granuloporous + fibrosoradiated + palisaded) which does not occur in urinary stones and it may also form a structure which we call "concretioning" which has not previously been described.

Aged↗
PubMedDate not supplied

[Ultrastructure of primary or endogenous prostatic calculi. Scanning electron microscopic study].

We make an analysis by means of a Scanning Electromicroscope, of the ultrastructure of 15 Primary Prostate stones. The components identified were: Carboapatite in 14 stones, Hydorxyapatite in 3, Whitlockite in 4 and Wedellite in 2 stones. The ultrastructural findings have enabled us to classify them as follows: 1. Hydroxyapatite stones, which we call "Crystalline", the rarest, due to the predominance of the inorganic component. 2. Carboapatite stones, which possess a great deal of organic material and which we subdivide into "Amylaceous" for those which possess some ovoid formations which appear to us to correspond to amylaceous bodies and "non-amylaceous" for those without them.

Apatites↗
PubMedDate not supplied

[Mixed-nucleus renal calculi].

We made a crystallographic analysis of 87 mixed-nucleus stones and found 4 groups of stones of this kind, which are as follow: urico-oxalic, oxalico-uric, phosphato-oxalic and oxalic-phosphatic. We did not find any mixed-nucleus, urico-phosphatic or phosphatico-uric stones and we explain this fact according to the known lithogenic, metabolic mechanisms, in which urinary pH has an important function.

Apatites↗
PubMedDate not supplied

[Clinical behavior of mixed nucleus reno-ureteral calculi].

We made a statistical study, by means of a computer, of 87 crystallographically-analysed stones, corresponding to 85 patients, assessing different clinical data with the mixed composition of the nucleus of these stones. We deduce that in general, the behaviour of these stones is determined by the interaction of their components, with the main substance predominating. The most significant correlations were obtained when we assessed the sex, age, urinary infection, simple or coralliform morphology of the stone, the number of stones formed, permanent, homolateral, kidney damage, overall kidney failure and procedure for removing the stone. We did not find any valid links when we compared the family record of lithiasis, affectation of the counterlateral kidney and the fact whether the stone was from the right or the left.

Adolescent↗
PubMedDate not supplied

[Seasonal effect of age, sex and drinking water composition on nephritic colic].

The influence of the season, age, sex and composition of the drinking water on the incidence of kidney colics in patients of different villages, attended at the "San Cecilio" Clinical Hospital in Granada, is assessed. The average, of kidney colics per 1.000 inhabitants was 4.2% with 51.27% in females and 48.73% in males. We found that in the summer months the frequency of kidney colics was double that in the winter months, which may be due to a relative D hypervitaminosis, a greater intake of oxalates or a relative dehydration. No influence of the calcium, magnesium, chlorine and sulphate contents of the water, was detected. In some villages, a high calcium and magnesium content in the water, posed problems for the urolithogenic prophylaxis in some patients.

Adolescent↗