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Biomedical subjects

J Algaba Guimerá

Publications and source records attributed to J Algaba Guimerá.

17 recordsLinked to original sources

[Evaluation of the fine needle aspiration biopsy in the presurgical diagnosis of tumors of the parotid gland].

The treatment ofparotid masses is generally surgery. The presurgical assesment is made by clinical examination, radiology and fine needle aspiration (FNA). FNA has been applied for the last decades and has been the subject of many reviews. It is a safe, rapid and economic procedure that can be made as an ambulatory procedure. In this study we have reviewed the parotidectomies performed in our institution during the years 1998 - 2003 where a preoperative FNA was available. The sensitivity of FNA in our hands is 40% and specifity 96.3%. We have also calculated the utility of clinical examination and radiology in the assessment of parotid masses.

Adolescent↗

[Immunohistochemistry study of EGFR expression in head and neck squamous cell carcinoma].

EGFR is an important transmembrane receptor member of the family of tyrosine kinases, that translates signals from both outside and inside the cell and plays a key role in numerous proceses that affect tumour development, growth, progresion, differentiation, inhibition of apoptosis and metastasis. Immunohistochemistry studies have shown that 40-80% of head and neck squamous cell carcinomas express EGFR and it has been suggested as a potential independent prognostic parameter. The objective of this study is to evaluate by immunohistochemistry the expresi6n of EGFR in a series of Head and Neck Squamous Cell Carcinoma and correlate it to clinico-pathological features and prognostic significance. We investigated expression of EGFR in 44 samples. There was a high expression in 41% of the cases. Even if we have not found that the expression of EGFR correlated with the prognosis of these patients the presence of EGFR is very important because there are chemical agents or drugs that can inhibit its activity.

Aged↗

[Palpation and CT to evaluate the cervical adenopathies in head and neck tumours].

Lymphatic metastasis is an important prognostic factor in patients with head and neck squamous cell carcinomas. Diagnostic evaluation and treatment of this adenopathies is very important. We can use physical examination, computered tomography (CT), magnetic resonance, ultrasound... but none of these give us a 100% security. This study evaluates the accuracy of physical examination and CT in detecting cervical lymph nodes. 120 neck dissections were performed after palpation and CT of 72 patients with head and neck carcinoma. Sensitivity of palpation was 51.7 and specificity 96.7. CTs sensitivity was 65 and specificity 86.7. Both, physical examination and palpation have a high number of mistakes evaluating cervical nodes. N0 necks are still a problem for Head and Neck Surgeons.

Head and Neck Neoplasms↗

[Stapedectomy as day case surgery].

Day case surgery is increasing and a large proportion of procedures in otolaryngology are already being performed as day cases. There is less experience in otologic surgery and the reports are specially referred to chronic otitis media. A retrospective study of stapedectomy as a day-case procedure is presented in this report. The inclusion criteria: anaesthesic risk: ASA I, II or III; if the patient has a chronic disease it must be well controlled; they must not have postoperative hemorrhagic history; the patient must be accompanied by an adult the first 24 hours postsurgery; must have a vehicle; distance to hospital must not be more than an hour and they must have a telephone. Between October 1998 and December 2002 71 ambulatory stapedectomies were performed in our institution. 91.2% were discharged home the same day of the procedure. Audiological findings obtained six months after surgery that: 87.5% of the patients have an air-bone Uda of 10 dB or less.

Adult↗

[Prevalence of exostoses among surfers of the Basque Coast].

Exostoses of the External Auditory Canal are benign bony tumours very common in individuals who frequently practice water activities. The objective [corrected] of this study is to determine the prevalence of exostoses in a population of surfers of the Basque Coast. We have studied the correlation between years surfing and the prevalence and severity of exostoses. We have done a cross-sectional epidemiological study giving a questionnaire Twenty-five of the 41 surfers had surfer's ear (61%) and the prevalence was significantly higher in those who had surfed for more than 10 years (p < 0.05). Severity was also higher in the first group (p < 0.05). The relation between the hours dedicated to the sport showed similar results. only one of the 24 cases needed surgery (4%).

Adult↗

[Treatment with CO2 laser of premalignant glottic epithelial lesions].

Pre-malignant lesions of the larynx can degenerative into invasive carcinoma. There is not an universally accepted classification and treatment. We present our experience in the treatment with endoscopic CO2 laser for the pre-malignant glottic epithelial lesions. At the same time we carry out a review of the literature published. During a period of ten years we have treated 69 patients with one of these techniques: resection of the epithelial lesion or vaporization. The election of the technique depends on the size of the lesion, the macroscopic aspect, anterior commissures involvement and the surgeons experience. The histological findings were: 53.6% keratosis and 23.2% mid dysplasia both of them treated with vaporization and resection; 14.5% moderate dysplasia and 8.7% severe treated with resection of the lesion. There were no important complications during the operation. Recurrence occurred in 7 patients (10%) but after treatment all of them were free of disease during the follow-up period, they didn't progress to carcinomatosis. 9 patients (13%) had a malignant evolution: 3 keratosis, 1 mild dysplasia, 3 moderate dysplasia and 2 severe dysplasia. Only one case (1.5%) underwent total laryngectomy. The early diagnosis and an appropriate treatment reduced the possibilities of malignant transformation. The therapy with CO2 laser is the treatment of choice in this kind of lesions.

Adult↗

[Laser cordectomy without hospitalization. Is it a safe intervention?].

OBJECTIVE: To evaluate the safety of the CO2 Laser Cordectomy in the treatment of glottic carcinoma as a day-case procedure. MATERIAL AND METHODS: Retrospective study of a cohort of 30 patients with glottic carcinoma treated with CO2 Laser Cordectomy at our institution between 1999-2001 as a day-case procedure. RESULTS: There were no major complications and no patients required re-intubation. 90% of the patients were discharged the same day of the procedure. There were three unplanned admissions to the hospital but none of them were, in our opinion, the direct result of Cordectomy. These patients were discharged the next day. 100% of the patients answered that they would repeat the experience. CONCLUSIONS: CO2 Laser Cordectomy of the glottic carcinoma can be safely performed as an outpatient procedure if patients are selected according to specific day-case criteria.

Adult↗

[Malignant tumors of external ear. Review of cases in 1991-2001].

Carcinoma of the external auditory canal is a rare tumor. Owing to the rarity of this disease, the literature provides very few publications of series. There is not a widely accepted staging system. The lack of a standarized staging system impedes meaningful interpretation of the literature. It is very difficult to compare different treatment strategies and results. The study is a retrospective case review. Seven patients with external auditory canal malignancies were studied. We used the staging system proposed by Arriaga et al. for both the Squamous cell carcinoma and non-SCC. We describe the risk factors, the symptoms, the treatment and the outcome and prognosis for our patients.

Ear Neoplasms↗

[Recurrent respiratory papillomatosis. Our experience and literature review].

The recurrent respiratory papillomatosis is a benign lesion induced by virus, with predisposal factors not yet clear out. Several treatment have been used, being the endoscopic surgery with laser CO2 the most used technique. We present our experience with laryngeal papillomatosis patients operated with laser CO2 in the last 15 years. The high rate of recidive in the youth pattern and the possibility of malignant degeneration in the adults charactherises this patients. Meanwhile without not other concluyent works surgery will be the first therapeutic alternative, avoiding mutilant operations, and paying attention in detecting lesions suggesting malignancy.

Child↗

[A bronchogenic cervical cyst. A case report].

The bronchogenic cyst is a tracheobronchial tree congenital malformation, normally intrathoracic. Usually presenting as an acute respiratory insufficiency (especially during infancy) or as recurrent respiratory infections or may be an accidental finding in asymptomatic patients. We present a rare case of cervical localization which began as an acute respiratory distress following a tonsilar infection.

Adult↗

[Mediastinitis secondary to Ludwig's angina. One case report].

Ludwig's angina is a cellulitis, usually of odontogenic origin, involving the submandibular space. The number of cases has been heavily lowered since the introduction of antibiotherapy. The treatment consists in an aggressive antibiotherapy and, sometimes, surgical drainage. Complications are: acute respiratory obstruction and spreading of the infection through the neck spaces till the mediastinum. We report one cas complicated with mediastinitis which diagnosis was based in radiological data, basically provided for TAC, The treatment required surgical drainage and antibiotherapy.

Adult↗

[Necrotic sialometaplasia of the hard palate].

Necrotizing Sialometaplasia is an intrabucal bening pathological change, clinically presented as an ulceration of the hard palate. Either clinically or histologically its resemblance with an squamous carcinoma offers heavy problems of differential diagnosis. The process heals spontaneously in different periods of time. The AA. present 2 cases diagnosed at their Department.

Adult↗

[Surgical treatment of exostosis in the external auditory canal].

Exostoses of the external auditory canal are benign bony tumours very common in individuals who frequently participate in aquatic activities. Although most of the cases are asymptomatic, patients with more severe exostoses have recurrent episodes of external otitis and related conductive hearing loss. In the great majority of these cases, a medical treatment (aspiration and antibiotic drops) resolves the symptoms. Patients with more severe canal stenosis, resistant to medical treatment, are candidates for surgical removal of the exostoses. This report reviews our surgical experience with 45 patients, 52 ears, who have undergone surgical removal of exostoses in our Institution during the last 13 years. We describe the technique that we use a well as the results that we achieve.

Adult↗

[Retropharyngeal hydatid cyst].

We report the case of a 37 year old male from rural area who presented as an emergency with symptoms compatible with the existence of a retropharyngeal tumoration. By the clinic it suggested an abscess but the CT scan as compatible with a carcinoma. On complementary examinations it appeared in a chest X ray an image which strongly suggested the possibility of a hydatidic cyst of the lung. Specific serologic reactions supported this and post-surgical pathological study lately confirmed the diagnosis. We believe of interest reporting this case because of it's unusual localization and difficulty in diagnosis.

Adult↗

[Acute respiratory obstruction caused by laryngeal rheumatoid arthritis].

We present a case of acute upper airway obstruction due to cricoarytenoid arthritis in severe rheumatoid arthritis. Although laryngeal involvement is common in severe rheumatoid arthritis, the upper airway obstruction is a very rare complication. The endotracheal intubation may be very difficult in these patients, thus fiberotopic bronchoscopy may be useful. Surgery is the final treatment.

Aged↗