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Biomedical subjects

J Alvarez-Coca

Publications and source records attributed to J Alvarez-Coca.

11 recordsLinked to original sources
PubMed1987

[Primary peptic ulcer in childhood: apropos of 16 cases].

We report a retrospective review of primary peptic ulcer disease in 16 children, 8 boys and 8 girls between 2 and 14 years of age, seen at our hospital over a 4 years and 4 months period. Endoscopy was realized in all children and revealed 7 duodenal ulcers (DU) and 11 gastric ulcers (GU) (two patients had both locations). At the initial diagnosis 5 patients were less than 6 years old with a ratio GU/DU of 4:1; in the other patients this ratio was 1:1. In children with duodenal ulcer 56.5% of them had positive family history. The commonest presenting symptoms were abdominal pain (87.5%) and acute gastrointestinal bleeding (68.7%). The follow-up period ranged from 2 to 52 months; in 13 cases follow-up was more than 1 year. Four patients (3 DU and 1 GU) older than 6 years recurred.

Adolescent↗
PubMed1985

[Trisomy 5p: a report of 2 cases].

Authors report two patients from different families who present similar abnormalities caused by an "almost complete" trisomy of the short arm of chromosome 5 [case No. 1: 46, XY, der (20), t (5; 20) (p11;p13), mat; case No.2: 46, XY, dup (5p)]. Several family members of case No. 1 were balanced translocation carriers. Case No. 2 is probably due to de novo duplication. Clinical findings in our cases and those cited in the literature allow identification of certain main features characteristic of "almost complete" trisomy 5p: hypotonia, weak cry, mongoloid slant of eyes, epicanthus, depressed nasal bridge, auricular anomalies, bilateral cryptorchidism and, less frequently, macrocephaly, micrognathia and club feet.

Abnormalities, Multiple↗
PubMed1984

[Right cervical aortic arch: report of 2 cases, one associated with aortic coarctation].

Cervical aortic arch is a rare congenital vascular anomaly. Usually it appears as an asymptomatic pulsatile cervical mass, but symptoms of tracheal and esophageal compression may be present in 25% of the patients. About 40% of cases are associated with vascular or heart abnormalities. Angiography provides definitive diagnosis. Authors report two patients with right cervical aortic arch, one of them associated with aortic coarctation, and review 52 published cases.

Aorta, Thoracic↗
PubMed1983

[Meningitis associated with congenital dermal sinus].

Three cases of congenital dermal sinus associated with recurrent meningitis are presented. Severe neurological sequelae were seen in the three patients because diagnosis was done too late. Authors emphasize the necessity of doing in these patients a meticulous visual exploration of the middle line on the skin from occipital to coccyx zones searching some defect in order to perform myelography and to make an early extirpation of the intraspinal tumor and to close congenital dermal defect.

Child↗