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Biomedical subjects

J Alvarez-Coca González

Publications and source records attributed to J Alvarez-Coca González.

5 recordsLinked to original sources

[Transient biliary lithiasis associated with the use of ceftriaxone].

Up to 40% of ceftriaxone is excreted unchanged into the bile and, due to its high calcium-binding affinity, it may form a salt that can provoke biliary lithiasis. Echography revealed that biliary lithiasis was present in 12-45% of patients treated with ceftriaxone as early as the second day of treatment. Lithiasis is usually asymptomatic and disappears in less than 2 months. Symptomatic cases and patients requiring cholecystectomy have been described in the literature. We present four children, evaluated in 1999, who presented asymptomatic cholelithiasis between the second and fourth day of ceftriaxone treatment. Biliary lithiasis was found after 2-4 days of treatment, with resolution of the lithiasis between 1-4 months after the end of therapy.

Ceftriaxone↗

[Cavernous hemangioma of the scrotum].

OBJECTIVE: To describe a case of scrotal cavernous hemangioma. METHODS: A 4-year old boy with a painful left scrotal mass is described. The epidemiology, natural history, diagnosis, differential diagnosis, treatment and prognosis of this tumor are reviewed. RESULTS: Analysis of the surgical specimen disclosed a scrotal cavernous hemangioma. CONCLUSIONS: A scrotal mass diagnosed at an uncommon age or atypical site warrants considering hemangioma as a possible etiology.

Child, Preschool↗

[Present-day status of glycogenosis Ib. Report of a new case].

A four-month-old boy affected by glycogen storage disease type I is presented. The child suffered from hepatomegaly, lactic acidosis, fasting hypoglycemia and failure to thrive. He had repeated infectious and cyclic neutropenia. Immunoglobulin and chemotactic neutrophil motility was impaired. Liver biopsy showed increased amounts of glycogen in hepatic cells as assessed by morphological and biochemical grounds. The activity of glucose-6-phosphatase as well as other glycogenolytic enzymes was normal in the frozen liver. The aforementioned characteristics suggested the diagnosis of glycogen storage disease type Ib. The child was first treated by enteral continuous feeding and later on by frequent meals during the daytime and enteral continuous feeding during the night time, improving the hypoglycemia as well as the other biochemical and metabolic abnormalities.

Biopsy↗