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Biomedical subjects

J Alving

Publications and source records attributed to J Alving.

5 recordsLinked to original sources
PubMed1979

'alpha pattern coma' following cerebral anoxia.

In 30 patients, who were all comatose as a result of cerebral anoxia after cardiac arrest, at least one EEG with activity in the alpha frequency range was recorded. Regionally the activity of the above mentioned characteristic was often diffusely distributed or most pronounced occipitally, whereas a tendency to affect other regions was rarely observed. In 50% of the patients, where more than one EEG was recorded, the 'alpha' rhythm was still present in the following record. Only one of the patients survived, and even so, with considerable mental defects. In 4 patients the level of consciousness improved, but 3 of them never reached a definite level of cortical function and died as a result of cerebral anoxia.

Adult↗
PubMed1979

Classification of the epilepsies. An investigation of 402 children.

The frequency distribution of different types of epilepsy (according to the classification model of the International League against Epilepsy) concerning 402 children is reported. The investigation showed a moderate preponderance of partial as against generalized epilepsies. Elemental and complex symptomatology were about equally frequent. As regards generalized epilepsies, the petit mal group was considerably smaller than most often reported previously; conversely, myoclonic-astatic epilepsy (Lennox-Gastaut's syndrome) was more frequently encountered. The definitory criteria and the concept of the Lennox-Gastaut Syndrome are discussed. 91.8% of the whole pediatric population (age less than 15 years at time of investigation) could be categorized according to the classification model. This, in agreement with earlier investigations on this subject, shows the contemporary international classified model to be useful and relevant.

Adolescent↗
PubMed1978

Classification of the epilepsies. An investigation of 1,508 consecutive adult patients.

The relative frequency of different types of epilepsy in accordance with the International Classification of Epilepsies is reported, concerning 1,508 consecutive outpatients with epilepsy, who at the time of investigation were at age 15 years and above. The investigation showed a marked preponderance for partial epilepsies as against generalized epilepsies; partial epilepsies with complex symptomatology were especially frequent, contributing by more than one third of all cases.

Adolescent↗
PubMed1977

Chromosome studies of bone marrow cells and peripheral blood lymphocytes from diphenylhydantoin-treated patients.

Chromosome studies were performed on both bone-marrow cells and peripheral blood lymphocytes from ten patients with epilepsy, treated with diphenylhydantoin alone. There was no evidence of chromosome damage. Furthermore, the bone-marrow smears from five of the patients were studied for the presence of micronuclei. There was no increase in the number of micronuclei compared with control persons. Conflicting results about the cytogenetic effect of diphenylhydantoin have appeared in the literature. It is emphasized that, in studies on the chromosome-damaging effect of chemical agents in man, bone marrow cells seem to be most indicative of the conditions in vivo.

Adult↗