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J Andris

Publications and source records attributed to J Andris.

5 recordsLinked to original sources
PubMed1999

Characterization of the three immunoglobulin G subclasses of macaques.

Southern blot experiments with genomic DNA samples of rhesus monkeys and crab-eating macaques and human C gamma-specific probes indicated that the two macaque species studied here possessed three C gamma genes per haploid genome. By amplifying the cDNA from macaque-mouse hybridomas, the coding sequences of two different rhesus monkey immunoglobulin (Ig)G subclasses, IgG1rh (Cgamma1rh) and IgG2rh (Cgamma2rh), and one crab-eating macaque IgG subclass IgG1mafa (Cgamma1mafa), were characterized. None of the 16 rhesus monkey-mouse hybridomas studied here secreted IgG of the third subclass IgG3rh (Cgamma3rh). The Cgamma3rh gene was partly characterized at the genomic level. The cDNA of the Cgamma3rh gene was amplified from mRNA of rhesus monkey peripheral blood mononuclear cells (PBMC). The results are analysed in terms of phylogenesis of the C gamma genes. The cDNA sequences coding for the Cmu and the Ckappa domains of rhesus monkey Ig were established and compared to their human and non-human primate counterparts.

Amino Acid Sequence↗
PubMed1990

Heavy chain variable region gene utilization in human antibodies.

We have sequenced by the polymerase chain reaction the heavy chain variable regions of over thirty human antibodies of defined specificity. The distribution of VH families in this group of antibodies is disproportionately skewed toward the recently discovered VH gene families. Within a family, there is also a disproportional use of individual gene segments. Numerous explanations for these imbalances are discussed.

Autoantibodies↗
PubMed1975

[Statistical analysis of 92 orthodontic cases].

A comparison has been made within 92 children who were either observed or treated by extractions or by orthodontic appliances and submitted to statistical analysis. Conventional treatments do not influence the skeletal structures except for the convex faces which are favorably modified by plate. The changes of the dental axis varied according to the dental group. The growth direction of the anterior facial structures seems to be constant amongst all considered children.

Bicuspid↗