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J Anson

Publications and source records attributed to J Anson.

40 records · Page 3Linked to original sources

Effects of barbiturates on responses evoked by excitatory amino acids in slices of rat olfactory cortex.

A study has been made of the effects of ranges of concentrations of phenobarbitone, pentobarbitone and thiopentone on responses evoked by gamma-aminobutyric acid (GABA), L-glutamate, L-aspartate, N-methyl-D-aspartate, kainate and quisqualate in slices of olfactory cortex of the rat. All three barbiturates affected GABA-evoked depolarizations similarly in that responses were potentiated by small doses but markedly inhibited at greater concentrations. Responses to L-aspartate and L-glutamate were little affected except at the largest dose of phenobarbitone tested (10 mM). The responses evoked by the selective agonists of excitatory amino acid receptors were inhibited by the barbiturates, the relative sensitivities being quisqualate greater than or equal to N-methyl-D-aspartate greater than or equal to kainate with phenobarbitone, quisqualate greater than or equal to kainate greater than N-methyl-D-aspartate with pentobarbitone and quisqualate greater than kainate = N-methyl-D-aspartate with thiopentone. The possible significance of these findings is discussed.

Amino Acids↗

Delayed abortion among teenagers: can a population at risk be identified?

Although only a small proportion of abortions performed in the United States are second-trimester abortions, teenagers obtain a large percentage of them. Yet the literature on abortion seekers is remarkably lacking in a discussion of who the pregnant teenagers who seek abortions are, particularly those who seek second-trimester abortions. We report a study of 97 adolescents who turned for help to a public abortion clinic in Missouri during 1989. We examined the impact of demographic variables, social-behavioral variables, and pregnancy-related variables (pregnancy, contraception, and abortion histories and attitudes toward abortion) on the stage of pregnancy at which the teens arrived at the clinic. Only contraceptive use and a positive attitude toward abortion were predictive of late arrival at the abortion clinic.

Abortion, Legal↗

The second dimension: a proposed measure of the rectangularity of mortality curves.

"The present paper proposes a measure of the shape (rectangularity) of the mortality curve which is statistically orthogonal to (independent of) the level of mortality over a broad range of national life tables, both historical and contemporary.... We have proposed [using]...a ratio of survival probabilities in two broad age ranges, in middle and young adulthood. It is suggested that this measure is an effective first approximation, which can be built on both methodologically and substantively, in order to obtain a better understanding of the social and other conditions producing rectangular and troughed mortality curves." Data for selected developed countries are used to test the model. (SUMMARY IN FRE AND ITA)

Age Factors↗