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Biomedical subjects

J Antonelli

Publications and source records attributed to J Antonelli.

10 recordsLinked to original sources

Solvents and color discrimination ability. Nonreplication of previous findings.

Previous research has shown exposure-related increases in the prevalence of acquired color vision deficits among printers. We administered the Lanthony D-15 desaturated test of color vision to 82 print shop workers. Two tests of cognitive function, Trails A and B and the Symbol Digit Modalities Test, were also administered. Personal air sampling indicated that current exposure to organic solvents was highest among printers and lowest among bindery workers. In contrast to previous studies, the age-adjusted quantitative Lanthony D-15 desaturated test error scores did not differ significantly between exposure groups, and the proportion of subjects with > or = 1 error was greater in the lower-exposure, rather than higher-exposure, groups (P = .03). Of note, the proportion of subjects with > or = 2 errors did not differ significantly between groups (P = .24). Cognitive tests showed no significant association with exposure. These results are discussed in the context of methodological issues related to lighting sources, reliability of test results, and establishment of criteria for identifying deficits.

Adult

Further delineation of the acrocallosal syndrome.

The acrocallosal syndrome (ACS) was recognized by Schinzel in 1979 as a specific entity, characterized by the association of craniofacial anomalies, total or partial agenesis of corpus callosum, polysyndactyly and mental retardation. The inheritance is autosomal recessive, based on instances of recurrence in siblings and cousins and parental consanguinity. A large inbred kindred with recurrent ACS is presented. This family further strengthens the hypothesis of autosomal recessive inheritance for this syndrome. The array of clinical manifestations in this sibship and those previously reported exemplify the phenomenon of inter- and intrafamilial variability that must be considered when defining ACS. Based on a review of published reports and the present family, essential, additional and occasional findings are distinguished. Attention is drawn to geographical clustering of the families.

Abnormalities, Multiple

Noonan's syndrome associated with hypoplastic left heart.

A case of a week old female baby, admitted because of apathy, hypothermia, dyspnea, jaundice and cyanosis is described. She had the characteristic phenotype of Turner's syndrome with normal karyotype. Signs of severe heart failure were present. Therapy with diuretics, digoxin, dopamine and mechanical ventilation were unsuccessful, and the patient died several hours after her admission. The anatomopathological examination revealed the presence of hypoplastic left heart syndrome with mitral atresia and aortic atresia, atrial septal defect, double outlet right ventricle, and a patent ductus arteriosus.

Abnormalities, Multiple

[Toxocariasis in Emek Israel].

Toxocariasis is a rare zoonotic disease in Israel. It usually affects children under the age of 10. Toxocara canis and Toxocara catis are common parasites among dogs and cats which affect man when he ingests the eggs of these helminths. We describe 3 children with different clinical presentations of the infestation. A 6-year-old boy had pain in the muscles of the limbs and diffuse patches in the right lower lobes on X-ray; a 7-year-old girl presented with a limp; and a 3-year-old boy had abdominal pain and a maculopapular rash covering the whole body. All 3 had eosinophilia. They illustrate the importance of toxocariasis in the differential diagnosis of eosinophilia.

Child

Cardiovascular malformations in lecanosomatopagus conjoined twins: a cardiologic curiosity.

Female conjoined twins were delivered after 42 weeks' gestation, but they died within a few minutes of birth. They were dicephalus, dibrachius and dipus conjoined twins with two separate spines and fusion of the trunk and the pelvis. The pericardial sac was common, and the heart was a single structure. The atrial complex was a common chamber with an attempt at division into two parts by a circular ridge of tissue; the ventricular complex was formed by three chambers which were all communicating between each other in the superior margin of their muscular interventricular septum.

Abnormalities, Severe Teratoid

Antimicrobial properties of dental dentin-enamel adhesives.

This study evaluated the antimicrobial activity of Universal Bond II adhesive and two experimental versions of Universal Bond II adhesives against the bacteria, Streptococcus mutans. The zones of bacterial inhibition produced by three samples of the adhesive (identified as Batches 1, 2, and 3) were measured and compared. Batch 1 contained 0.7% glutaraldehyde, Batch 2 contained 1.0% glutaraldehyde, and Batch 3 contained 0.45% glutaraldehyde (current Universal Bond II adhesive). The bacteria was swabbed over the surface of agar plates in two directions. The plates were divided into the following two groups: Group I-Batches 1, 2, 3 were placed into wells for 1 minute before being cured. Group II-Batches 1, 2, 3 were placed into wells for 20 seconds before being cured. Zones of microbial inhibition were measured in millimeters at the end of 24, 48, and 72 hours. All batches of the adhesive produced zones of inhibition against S. mutans. All batches of the adhesive maintained zones of inhibition throughout the 72 hours of the study.

Adhesives