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Biomedical subjects

J Apitz

Publications and source records attributed to J Apitz.

At least 73 records · Page 4Linked to original sources

[Propranolol in Fallot's tetralogy: hemodynamic investigations and their clinical use (author's transl)].

During heart catheization in 32 non-selected patients with Fallot's Tetralogy the reaction of O2-saturation, right-to-left-shunt and of cineangiocardiography to 0.2 mg/kg propranolol i.v. was tested. Nine of 32 patients reacted favourably to propranolol. Of these 6 were put on a long term-medication of 2 to 3 mg/kg propranolol orally. Only 1 patient did not respond satisfatorily. The effect of propranolol and hemodynamic results are compared with the literature and discussed. In Fallot's Tetralogy propranolol medication without previous testing ist not recommended: without previously established exact diagnosis it can be dangerous even.

Adolescent↗

[Risks and results of banding surgery (author's transl)].

A Muller-Dammann banding operation was performed in 64 infants and small children within 5 years. The diagnosis and the surgical risk (between 5.9% and 65% depending on the degree of intracardial malformation) were presented. Complications and cause of death were described and compared with data presented in the literature. Twenty-three patients were given a follow-up examination with special cardiac diagnostic methods. The hemodynamic results were compared with those from 9 children who were operated on late. As other authors, were also found a pronounced reduction in pulmonary flow in those children operated on early and not in those operated on late.

Follow-Up Studies↗

[Transumbilical heart diagnosis and ballon atrioseptostomy].

The way of catheter insertion through the umbilical vein is presented. We attempted the transumbilical heart catheterization in 63 patients, in 14 we failed to make an exact diagnosis. Furthermore, in 17 out of 26 patients we could perform the balloon atrial septostomy transumbilically. The possible complications are discussed and this access is recommended as an elegant and time-saving method.

Cardiac Catheterization↗

[Mitral valve prolapse or late systolic click syndrome in childhood].

6 Children with late systolic murmur and systolic click in mitral valve prolapse syndrome are reported. The clinical, electrocardiographic, phonocardiographic and echocardiographic findings are represented. In differentiating the mitral valve prolapse from the idipathic hypertrophic subaortic stenosis, the mitral insufficiency and the pure accidental murmur, this non-invasive technique is a good enrichment of the diagnostic procedures.

Adolescent↗

[Cardiovascular malformations in embryofetal alcohol syndrome (author's transl)].

17 infants and children with embryofetal alcohol syndrome were examined of cardiovascular malformations. In 8 cases heart catheterization revealed malformations, mainly atrial septum defects (in 5 of 8 cases), only in one case a ventricular septum defect, in another case an aplasia of the right pulmonary artery and in one case a mild outflow tract obstruction of the left ventricle. Congenital heart diseases can be expected in nearly 50% of the cases in embryofetal alcohol syndrome.

Alcoholism↗

[The correlation between pulmonary hypertension and histological findings of the pulmonary vessels in congenital heart disease (author's transl)].

In nearly 100 infants the hämodynamic and histological findings of pulmonary hypertension in congenital heart diseases are correlated when a banding-procedure was done. There were: 45 ventricle septal defects, 10 atrio-ventricular canals, 13 transpositions of the great arteries, 16 patent ductus arteriosus and 7 miscellaneous. A hämodynamic hypertension was more frequent than the histological hypertension; but there was a difference in the different heart diseases: The patients with patent ductus arteriosus and hypertension show only in a few cases histological alterations; in infants with VSD the correlation was much more better. Whether a banding procedure of the pulmonary artery is able to provide the progress of pulmonary sclerosis may be discussed after a second excision of lung-tissue when the correction of the heart disease is done.

Age Factors↗

[Aberrant pulmonary vessels from the abdominal aorta in children with congenital heart disease (author's transl)].

Ten children are described in whom aberrant pulmonary vessels arising from the abdominal aorta were found in the course of cardiac investigations. In five, sequestrated lung, as described Pryce, was demonstrated; in the others, these vessels were found incidentally without any demonstrable abnormality in the lung. Our findings indicate that one must distinguish between aortic pulmonary vessels with and without pulmonary sequestration during childhood. The need for deliberate opacification of the aorta is pointed out. This is also necessary in arriving at the indications for sergery. In the presence of congenital heart defects, these arterial vessels are found particularly in the presence of hypoplastic lungs and with the scimitar syndrome (3 cases).

Abnormalities, Multiple↗