[Early functional evaluation and physical rehabilitation in patients with wide myocardial infarction (author's transl)].
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Biomedical subjects
Publications and source records attributed to J Assandri.
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The physiopathological mechanisms of the different degrees of the Acne Vulgaris are reviewed. The observations show the important antigenic activity of the "Propionibacterium acnes" and the cellular immunity in the inflammation. An immunologic concept could explain this process.
Four cases of subjects with implanted pacemakers are reported. The patients temporarily presented suspected symptoms of altered activity of the pacemakers. On the other hand usual tests demonstrated a regular activity of the pacemakers. The dynamic electrocardiography, by a regular registration during 24/48 hours and during usual working, documented; once a partial hole in the circuits of the generator, twice a partial break of the catheter, once a displacement. It is underlined the importance of dynamic electrocardiography to identify temporarily altered activity of pacemakers, undiagnosticable by disposable usual tests.
The biochemical properties of the Propionibacterium acnes in 22 patients with inflammatory Acne vulgaris was studied. Group I/II was found in most cases. There was no difference between the biochemical properties of the comedone and the pustule. The authors suggest that factors other than those depending on the PA degradative metabolism can be responsible for the purulent inflammatory process of the pil-sebaceous follicle.
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The results of the same rehabilitation protocol are compared in two groups of patients with recent transmural myocardial infarction. The first group consists of 63 males, aged from 40 to 49 (mean 44.5); the second one of 63 males, aged from 60 to 74 (mean 64.7). The age is the only difference between the groups. The training does increase the mean value of the Total Work Performed from 5126 +/- 2201 to 7505 +/- 2455 Kgm (p < 0.001) in the young patients and from 3340 +/- 1414 to 4793 +/- 1598 Kgm (p < 0.001) in the old ones. The amount of increase is 46.4 and 43.5 per cent, respectively. The Heart Rate at fixed level of 75 W decreases from 125 +/- 2 to 119 +/- 1.6 beats per minute (p < 0.001) in the young group and from 119.2 +/- 2.2 to 111.3 +/- 2.2 (p < 0.001) in the old group of patients. The O2 Pulse at 75 W increaes from 8.8 +/- 0.2 to 9.7 +/- 0.25 cc per beat (p < 0.001) in the young subjects and from 9.4 +/- 0.4 to 10.3 +/- 0.4 (p < 0.001) in the old ones. The Double Product at 75 W decreases from 23.6 +/- 0.7 (X 10(3)) to 21.4 +/- 0.5 (p < 0.001) in the young patients and from 24.4 +/- 0.8 to 21.6 +/- 0.7 (p < 0.001) in the old ones. A control performed in 26 subjects of both groups 1 year later, shows a good persistance of the training effect as in young as in old patients. The AA. come to conclusions that: a) The age does not represent a limiting factor for the indication to the rehabilitation after a myocardial infarction; b) the rehabilitation can provide similar results in young and in old patients and the achieved benefits can be similarly maintained; c) the risk of any complication during training is higher in old than in young patients. It compels us to a careful choice of patients and control of the rehabilitation procedure.
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32 patients with different degrees of acne and 10 healthy controls were studied. On every one of them the test for lymphocytic transformation was performed looking for the range of blastogenic response, using PHA and CA. The positive findings with CA related to those obtained in normal subject would support the hypotesis that the cellular immunity as a response to CA antigens would be different in each patient according to the host local conditions.
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Five cases with angiocardiographically diagnosed posterior mitral valve prolapse and without ausculatotory findings of midsystolic click or late systolic murmur were studied with phonocardiographic technique employing pharmacological tests and postural changes. A midsystolic click was thus obtained. Isoprenaline was the must helpful drug to achieve it. The accompanying electrocardiographic and coronarographic features of this syndrome are described and discussed.
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The authors report fifty-nine cases of non-transmural myocardial infarction. The diagnosis was made on the basis of clinical electrocardiographic data and enzyme changes. The clinical course was characterized by several chest pain attacks; a transmural myocardial infarction occurred in four patients a few days after admission. Out of fifty-five patients, followed for a nineteen - months period, six died, thirty-one were asymptomatic and fourteen complained of angina. In the last group, chest pain was generally present before the non-transumural myocardial infarction. The ECG were within normal limits in thirty-seven patients. The coronarographic patterns found in fifteen patients are also described and discussed.
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