[Electrophoretic bidimensional analysis in polyacrylamide gel of the tuberculoproteins present in IP and in various other preparations of PPD].
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Acrylic Resins↗
Biomedical subjects
J Augier
Publications and source records attributed to J Augier.
[Various experimental diseases induced in guinea pigs by the historical Institut Pasteur BCG strain and by the B-1 positive catalase strain. Study of the viability of the inoculated bacteria].
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Animals↗
[Study of the specificity of fluorescence microscopy in the detection of acido-alcholo-resistant bacilli].
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Bacteriological Techniques↗
[Comparative solvent capacity of Brij 35 and Tween 80 in purified IP 48 tuberculoprotein adsorbed on the glass of ampules during lyophilization].
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Drug Stability↗
[Histopathologic study of the experimental pathogenic power of isoniazid-resistant BCG: fresh or lyophilized catalase-positive B1 strain].
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Animals↗
Preparation of tuberculin antigen L.
The preparation of antigen L using culture filtrates of live BCG is described. The procedure consisted essentially of precipitating this filtrate with 10% trichloroacetic acid in the presence of N-butyl alcohol 4% final concentration. The precipitate was chromatographed on carboxy-methyl-trisacryl-M and then on DEAE-trisacryl-M; in both cases, maximal biological activity (delayed-type hypersensitivity) was found in the void volume. The product thus obtained was chromatographed on a molecular sieve so as to eliminate poorly active fractions. The final product was 30-fold more active on guinea-pigs sensitized with live BCG than on those sensitized with inactivated BCG.
Animals↗
[Comparative bacteriological development in 2 groups of patients with severe pulmonary tuberculosis, 1 treated with a rifampicin-base combination, the other with an INH-base combination].
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Humans↗
[Bacteriological evolution established in 406 tuberculosis patients treated with various combinations with or without rifampicin or INH].
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Humans↗
[Fluorescent microscopy of the tubercle bacillus. II. Specificity of the method].
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Journal Article↗