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J B Arbuckle

Publications and source records attributed to J B Arbuckle.

At least 19 recordsLinked to original sources
PubMed1995

Expression of tetrodotoxin-resistant sodium channels in capsaicin-sensitive dorsal root ganglion neurons of adult rats.

We have used conventional whole-cell electrophysiological recording techniques to measure the level of expression of tetrodotoxin-sensitive (TTX-S) and tetrodotoxin-resistant (TTX-R) sodium currents in the capsaicin-sensitive and capsaicin-insensitive subpopulations of dorsal root ganglion neurons. We find that there are significantly higher levels of TTX-R expressed in the capsaicin-sensitive group but no difference in the levels of TTX-S. Since capsaicin is a selective stimulant of polymodal nociceptors, these data raise the possibility that TTX-R sodium channels may be an important determinant of nociceptor phenotype.

Animals↗
PubMed1978

A survey of thelazia worms in the eyelids of British cattle.

Thelazia skrjabini and T gulosa were found in the eyes of 237 of 566 bovine heads (41.9 per cent) examined in a Surrey abattoir during 1976. The prevalence of infection increased during late June, July and August, when a new generation of worms emerged in eyes. The burden in eyes ranged from one to 170 worms, with a mean count of 10.44 +/- 3.23. Worms were found behind and in third eyelids and in the lacrimal ducts of lower eyelids, which makes their detection very difficult by clinical examination. They were significantly more common in cattle 21 to 38 months old than in those less than 21 months old. Lesions occurred in 14 of 327 (4.3 per cent) infected eyes. No worms were seen in eye washings from cattle in nine herds experiencing outbreaks of keratoconjunctivitis.

Animals↗
PubMed1976

Observations on the association of pathogenic Escherichia coli with small intestinal villi of pigs.

Pathogenic Escherichia coli were observed in association with microvilli of piglets experimentally infected with E coli O149:K91,K88a,c, but the bacteria were only rarely observed actually in contact with microvilli. The association of E coli with villi occurred most commonly in the ileum and least commonly in the duodenum: in some pigs, it was only observed in the ileum. The proliferation of pathogenic E coli in the small intestine and their association with villi commonly coexisted, although each phenomenon was also observed independently. It is suggested that the villous association of pathogenic E coli is not a prerequisite for their proliferation.

Animals↗