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Biomedical subjects

J B Arnoult

Publications and source records attributed to J B Arnoult.

7 recordsLinked to original sources
PubMed1987

Effectiveness of botulinum toxin therapy for essential blepharospasm.

The effectiveness of Botulinum toxin (Oculinum) therapy in 76 patients with the diagnosis of essential blepharospasm was analyzed. Botulinum offers relief to almost all patients suffering from essential blepharospasm, however, this relief is usually temporary. The response time for repeated treatments tended to be longer than the first treatment. Patients with mild blepharospasm responded significantly longer to Botulinum injection, than those with severe spasms. The response to Botulinum was not significantly different in patients with Meige syndrome than in patients with only essential blepharospasm. Patients previously treated surgically for essential blepharospasm did not respond differently than those patients with no previous surgical therapy. The authors believe that Botulinum toxin injection is an effective, although temporary, mode of therapy for the signs and symptoms of this focal dystonia. The authors recognize that there may be psychologic factors affecting the response.

Blepharospasm↗
PubMed1979

Comparative evaluation of current ophthalmodynamometers.

Seventy-five patients under 40 years of age with no history of ocular, cardiovascular, or cerebrovascular disease were examined with four commonly used ophthalmodynamometers. There was a significant difference in the absolute values measured with each instrument and the ophthalmic to brachial artery pressure ratio. The standard deviations were comparable between 8.1 and 10.2%. The absolute value of the average percent difference between the right and the left eye ranged from 3.6% with the Galin unit to 6.7% with the Sisler unit. Limits of +/- 15% for ophthalmic artery to brachial artery pressure ratio and 10% for right to left pressure difference should be used for 95% confidence levels. There was a small but definite correlation between the ocular coefficient of rigidity and pressure differences between direct and indirect instruments.

Adolescent↗
PubMed1976

Comparative study of the surgical management of congenital esotropia of 50 prism diopter or less.

Fort-nine patients with congenital esotropia of 50 prism diopters or less were selected at random. Twenty-five had bimedial recessions performed initially followed by bilateral rectus resections when needed. Twenty-four had recession/resections performed initially and when needed, were followed by the same procedure on the fellow eye. The average corrections obtained after first procedure and after second procedure were compared and analyzed. The results showed the initial procedures of both groups to be equally effective. The results obtained after the second procedure in the recession/resection group were significantly better. Therefore, it would appear that for the patient we have described, the most effective surgical approach is ultimately the surgical regimen of recession/resection followed by the same procedure on the fellow eye.

Child, Preschool↗
PubMedDate not supplied

Goniotomy with sodium hyaluronate.

A modification of the classical goniotomy technique is described. After complete evacuation of the anterior and posterior chambers, sodium hyaluronate is placed in the anterior chamber and on the cornea. Putting hyaluronate in both locations prevents the formation of air bubbles under the goniotomy lens, provides the same index of refraction on both sides of the cornea, prevents accidental loss of the anterior chamber, and allows maximal depth of the anterior chamber. Diminished intraocular bleeding and lower risk of injury to the corneal endothelium, iris, and lens may be additional advantages of the procedure. Two cases are presented in which five goniotomies were performed on four eyes using this technique. Both patients had one eye controlled with a single goniotomy. The fellow eye of each patient required multiple procedures. Glaucoma was controlled successfully with no medication in all four eyes. No significant complications occurred.

Female↗