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Biomedical subjects

J B Bart

Publications and source records attributed to J B Bart.

9 recordsLinked to original sources
PubMed1987

Suppression of hemoglobin H in disorders of iron metabolism.

Disorders of iron metabolism affect the expression of hemoglobin H in hemoglobin H disease. Two cases of iron deficiency with reduced synthesis of hemoglobin H are described in the literature. We report two more cases, one with anemia of chronic disease and another with alcoholic sideroblastic anemia where the hemoglobin H was not detected at presentation and appeared after treatment of the underlying disorder. The pathogenesis of suppression of hemoglobin H is discussed.

Adolescent↗
PubMed1978

Recurrent hemolytic anemia secondary to acessory spleens.

A patient with recurrent hereditary spherocytosis due to a hypertrophied accessory spleen is presented. In patients in whom splenectomy is performed for hematologic disease, accessory spleens must be sought and removed. Recurrence of the inital disease should prompt a search for accessory spleens.

Adult↗
PubMed1976

The surgical and hematologic significance of accessory spleens.

The approximately 10 per cent incidence of accessory spleens in the general population is well documented, and accessory spleens often are not clinically significant. Trauma, torsion and, especially, hematologic diseases can affect an accessory spleen. A careful search should be made for accessory spleens, and they should be removed at the time of primary splenectomy so as to avoid a second operation later in life.

Adult↗
PubMed1975

Thrombocytopenic purpura in infectious mononucleosis-- A rare complication?

We have presented an illustrative case of thrombocytopenic purpura complicating infectious mononucleosis. Steroid therapy appeared to be beneficial although spontaneous recovery cannot be excluded. The use of the Paul-Bunnell heterophil agglutination test is recommended for patients having idiopathic thrombocytopenic purpura to rule out subclinical infectious mononucleosis. It is suggested that this syndrome be treated with the expectancy of long-term remissions. Steroids appear to be of benefit. Platelet recovery is usually complete in less than 60 days. Splenectomy should not be considered until at least two months have passed. Chronic thrombocytopenia is an unlikely complication.

Adolescent↗