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J B Brunet

Publications and source records attributed to J B Brunet.

52 records · Page 3Linked to original sources
PubMed1987

AIDS in Europe: current trends and short-term predictions estimated from surveillance data, January 1981-June 1986.

European AIDS surveillance data, reported to the World Health Organization (WHO) Collaborating Centre on AIDS, Paris by 30 June 1986, have been analysed statistically to assess current trends and to provide short-term predictions. Reported case numbers were first adjusted to allow for the estimated time delays between diagnosis and reporting. The adjusted data (cases per half-year of diagnosis) were then fitted using exponential functions over selected time intervals to monitor and compare the evolution of the epidemic in individual countries and in the European Community (EC) as a whole. Predictions to mid-1988 were made by extrapolation. Results are presented for the EC and for the following individual countries: Belgium, Denmark, France, Federal Republic of Germany, Italy, The Netherlands, Spain, Sweden, Switzerland and the United Kingdom.

Acquired Immunodeficiency Syndrome↗
PubMed1986

[AIDS surveillance in Europe].

By 30th September 1985, 21 countries were taking part in a network of AIDS surveillance in Europe. The data collected by each country are centralized in one of the WHO Collaborating Centres on AIDS, located in Paris (France). The cases reported are analysed according to sex, age, disease category, date of diagnosis, geographic origin, and distribution according to risk groups. The results of this surveillance enable the characteristics of this epidemic to be described in Europe and provide a useful tool for adapting public health strategies to the respective conditions in each country.

Acquired Immunodeficiency Syndrome↗
PubMed1985

The international occurrence of the acquired immunodeficiency syndrome.

Through December 1984, 9932 cases of the acquired immunodeficiency syndrome have been reported, mainly from North and South America and Europe; 85% of these cases occurred in the United States. Haiti and the United States have the highest incidence rates, 59 and 36 per million population, respectively. Rates in the United States range from 0.3 (beginning of 1981) to 10.4 (end of 1984). Brazil, Canada, Denmark, Switzerland, France, West Germany, the United Kingdom, and the Netherlands show a slower increase. Homosexual men and intravenous drug users are still the main risk groups in the United States and Europe. The disease is prevalent in heterosexual Haitians and Africans whether they live in their own countries or abroad. Cases of the syndrome have been identified in Zaire, Rwanda, Zambia, and Uganda, but its full extent is not yet known. Consistent with the general history of epidemics, the appearance of geographically separated sites of incidence of the syndrome could be linked to population migrations; however no evidence has been found to identify an index location.

Acquired Immunodeficiency Syndrome↗
PubMed1984

Adaptation of lymphadenopathy associated virus (LAV) to replication in EBV-transformed B lymphoblastoid cell lines.

A strain of lymphadenopathy associated retrovirus ( LAV ) passaged in vitro was used to infect a lymphoblastoid cell line obtained by transformation with Epstein-Barr virus of B lymphocytes from a healthy donor. The virus produced from this line (B- LAV ) was also able to grow at a high rate in some other lymphoblastoid lines and in a Burkitt lymphoma line. This adapted strain retained the biochemical, ultrastructural, and antigenic characteristics of the original strain, as well as its tropism for normal T4+ lymphocytes. It is thus possible to grow LAV in large quantities that can be used for the preparation of diagnostic reagents. The interaction between such a human retrovirus and Epstein-Barr virus, a DNA virus, may have some implication for the pathology of the acquired immunodeficiency syndrome and related diseases.

Acquired Immunodeficiency Syndrome↗
PubMed1984

[Acquired immunodeficiency syndrome: epidemiological data in France and throughout the world].

Nearly three years after the first A.I.D.S. cases were detected in the United States, a lot of countries throughout the world have reported varied numbers of such cases. While several U.S. towns have to face up to an epidemic situation, the same phenomenon has not been observed yet in the other areas, including European countries. In those latter countries homosexuals represent the most important group among patients. Two differences have to be noticed with the U.S. situation: numerous cases among patients from Equatorial Africa have been reported, and the disease has not spread over among I.V. drug abusers. Although no specific agent can be identified yet, A.I.D.S. features are characteristic of a transmissible disease.

Acquired Immunodeficiency Syndrome↗