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Biomedical subjects

J B Dubuisson

Publications and source records attributed to J B Dubuisson.

At least 181 records · Page 10Linked to original sources
PubMed1983

[Longitudinal salpingotomy and fertility. Experimental study in the female rabbit].

A microsurgical technique of salpingotomy has been put forward for the treatment of ampullary distal lesions responsible for infertility. --An experimental research has been carried out before proposing any application on women. --The consequences on the fertility of a female rabbit of a longitudinal salpingotomy followed by a microsuture have been thoroughly studied. --21 female rabbits have been operated under microscope. --In every case the tubal permeability has been maintained and the rabbits became pregnant. --In some cases histological lesions in front of the suture area have been noticed, what aroused several possibilities as to their origin.

Animals↗
PubMed1983

[Request for reversal of tubal sterilization. Survey conducted by the National College of French Gynecologists and Obstetricians].

A retrospective enquiry was carried out by the National College of French Gynaecologists and Obstetricians to try to specify more clearly indications and contra-indications for tubal sterilization in sixty centres. 377 requests were analysed over the years 1979-1980-1981. The average age of these women was 33 and the interval following sterilization was of a mean of 5 years. Remarriage is the main reason for asking. Those women most likely to ask for reversal of sterilization were patients who were sterilized when young or who had had only one or two children, or who had been sterilized during Caesarean operation. Half the requests for reversal could not be granted, usually because the techniques used for sterilization were too mutilating (40% of the patients could not be operated on); even if the sterilization is to be considered as final these techniques should not be used.

Adult↗
PubMed1983

[Microsurgical treatment of proximal lesions of the fallopian tubes. Apropos of 51 cases].

Microsurgical anastomosis was carried out on 51 patients who had proximal tubal lesions that were either purely isthmal, interstitial or isthmo-interstitial. 18-24 months later there were, using an actuarial method of calculation, 64% of intra-uterine pregnancies (+/- 2 X 8% skew) (line 8, Table IV). There has not been a single case of extra-uterine pregnancy so far. These results confirm the superiority of microsurgical anastomosis over implantation of the tube into the uterus.

Fallopian Tube Diseases↗
PubMed1982

[Exploratory salpingotomy].

One of the difficulties in tubal surgery concerning the distal portion of the tube is the accurate assessment of the value of the ampullary muscularis and mucosa on which depend the choice of the right operative procedure and the prognosis. The difficulties are most important in case of total terminal occlusion particularly when the site of the former ostium is no longer visible. An exploratory salpingotomy preceding any repair is made under the operating microscope. The simple technique that we describe allows: --an accurate assessment of the inner ampulla; --lysis of the mucosal adhesions inside the ampulla; --detection of the former ostium from the inside and the incision in the right place. The functional consequences of such an incision are difficult to appraise because the number of cases is so far too small and the follow up too short. However, those consequences seem slight when compared to the advantages, which are better precision in the investigation, the indication and the execution of the surgical repair.

Fallopian Tube Diseases↗
PubMed1980

Contact hysteroscopy: another method of endoscopic examination of the uterine cavity.

Recently there has been renewed interest in hysteroscopy which, since its discovery a century ago, has been in a state of uncertainty. Classical hysteroscopes all require the dilatation of the uterine cavity by the injection of a fluid under pressure. With contact hysteroscopy, the image is obtained by the applciation of the end of the apparatus against the uterine mucosa. This simplifies the equipment and opens up new possibilities. The results of more than 1,000 contact hysteroscopies done in the various circumstances of gynecology and the pathology of pregnancy are presented. The facility of this technique should contribute to the increased use of visual exploration of the uterine cavity, the advantages of which have already been shown.

Congenital Abnormalities↗
PubMed1979

[Early control laparoscopy after tubal microsurgery (author's transl)].

It is essential to carry out laparoscopic control to determine the result of plastic tubal surgery. This is classically done 12 to 18 months after the operation, yet it has been suggested that this control should be carried out earlier between the 4th and the 8th weeks or even on the 8th day following the operation. The authors have carried out 63 early control laparoscopies after microsurgical operations on the tube at different dates: 33 times between 4 and 8 weeks after the operation, 5 times between the 10th and the 13th day, and 25 times on the 8th day. They are in favour of early laparoscopic control with the reserve that it will require much more experience to tell whether the procedure is harmless.

Fallopian Tubes↗
PubMed1979

[Experimental study of the permeability of the fallopian tubes in the rabbit after division of the isthmus and microsurgical anastomosis (author's transl)].

The poor results of traditional reconstructive surgery of the Fallopian tubes have led the authors to try the possibilities of microsurgery in tubal sterility. The experimental animal chosen was the rabbit owing to its similarities with the Fallopian tube in women. After division of the isthumus, the tube was repermeabilised with a 10.0 single nylon thread under the operating microscope. A series of 11 rabbits were then coupled one mont after the operation. The pregnancy rate was 55%. This figure was much better than those obtained in the literature by non-microsurgical technics. One may hope to improve the results further by less traumatic surgery, better asepsis, and better control of fertility.

Animals↗
PubMed1978

[The antenatal diagnosis of haemoglobinopathies. A preliminary study (author's transl)].

From now on antenatal diagnosis of haemoglobinopathies is possible. Fetal blood can be taken from the uterus from the 17th to the 20th week of the pregnancy by direct puncture of the placenta or placentocentesis or by selective puncture of a straight vein close to its insertion in the cord on the fetal surface of the placenta, using a fetoscope. Biochemical techniques today allow us to detect beta thalassaemia major (with total absence of synthesis or with synthesis of less than 2 per cent of the beta A chain of haemoglobin by the fetus) and drepanocytosis (which is the synthesis of the chain beta S by the in the absence of production of the chain beta A). It is possible in cases where the fetal blood that has been taken is seriously contaminated by maternal blood (which is often the case with direct punctures) by using purification methods to increase the proportion of fetal red blood cells in the sample by eliminating adult reticulocytes which could cause errors in diagnosis. There are several centres where this type of diagnosis is being carried out. Some of them now have two years' experience and their results are encouraging. In spite of their difficulty these methods of investigation can allow couples at risk to have normal children or heterozygous infants. They can help them to avoid the need for termination of pregnancy or permanent contraception.

Anemia, Sickle Cell↗
PubMed1978

[Progress in the treatment of tubal sterility: microsurgery (author's transl)].

During the last few years microsurgery has evoked general enthusiasm in several surgical specialities and especially in plastic surgery. This is also true of gynaecology, where it is used for the surgery of sterility. Tubal microsurgery improves the results of operations by ensuring that the anatomical reconstruction shall be more precise and by lessening the amount of adhesions and secondary fibrosis. The first results that have been published prove this. The superiority of these difficult techniques is especially demonstrated by tubal recanalisations effected after sterilisation when the anastomosis is made in healthy tissue, being from the isthmus to the isthmus or from the isthmus to the uterus. Microsurgery is also the sole hope for the surgery of tubes that are at present inoperable. It will effect transplantation of the tube as soon as the problem of rejection has been solved.

Fallopian Tubes↗