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Biomedical subjects

J B Familusi

Publications and source records attributed to J B Familusi.

59 records · Page 4Linked to original sources
PubMedDate not supplied

The relationship between ventricular size and visual function in children with hydrocephalus.

We examined the relationship between ventricular size and visual function in 50 children (36 males and 14 females) with hydrocephalus. The third and lateral ventricular sizes and the visual function scores did not significantly differ between the sexes. Ventricular enlargement was most pronounced at the trigones and least at the level of the foraminae of Monro. The visual function score correlated inversely with the size of the lateral ventricle measured at the levels of the anterior horn and the trigone and expressed as coronal diameter and "Modified" Evans' ratio (r = 0.49; P = 0.001 and r = -0.38, P = 0.01 for the anterior horn; r = 0.48, P = 0.001 and r = -0.35, P = 0.001 for the trigone). The size of the third ventricle did not correlate with visual function score. A "modified" anterior Evans ratio of 0.60 and a trigonal Evans ratio of 0.73 were associated with very low visual function score. Furthermore, there was significant inverse correlation between occipitofrontal circumference (OFC) and visual function (r = -0.6379, P = 0.001), but OFC was not valuable for predicting visual function before the onset of head enlargement.

Accommodation, Ocular↗
PubMedDate not supplied

Low birth weight and its correlates among Nigerian twins.

The incidence and correlates of low birth weight (LBW) among an index population of 525 newborn Nigerian twins and a control population of 363 singletons were studied. The incidence of LBW among the twins (53.9%) was significantly higher than the incidence of 11.8% among the singletons (P < 0.001). Smallness for gestational age (SGA) was also higher (14.3%) among the twins compared with 1.4% among the singletons (P < 0.001). Morbidity factors frequently associated with LBW among the twins were perinatal asphyxia, hypothermia, neonatal seizures, and intracranial haemorrhage. Intrapartum asphyxia was particularly common in those preterm LBW twins who were also SGA. This raises serious concern because of the known higher risks of SGA preterm babies for severe neurologic sequelae. Low socioeconomic status (SES) of mothers was an important predisposing factor to LBW and SGA as well as to premature deliveries among the twins. Improved SES of the maternal population and increased awareness by health practitioners of the risks LBW twins face, should improve their immediate and later outcome. Furthermore, there is a need for the development of an intrauterine growth chart for Nigerian twins to enhance accurate diagnosis of LBW and SGA among newborn twins.

Asphyxia Neonatorum↗
PubMedDate not supplied

Hyperventilation-precipitated cerebrovascular accident in a patient with sickle cell anaemia.

Hyperventilation exercise during electroencephalography precipitated a recurrence of right hemiplegia and aphasia in a patient with Hb SS disease. Although recovery of function started within hours of the event, full recovery has not occurred six months after. Hyperventilation provocative test during electroencephalography should be discouraged in patients with sickle cell anaemia.

Adolescent↗
PubMedDate not supplied

Deficiencies in tetanus prophylaxis in wound management in Ibadan, Nigeria.

In a review of 94 paediatric patients treated for post-neonatal tetanus over a period of 11 years at the University College Hospital, Ibadan, Nigeria, reliable data regarding the care received for wounds that eventually resulted in tetanus was available in 58 patients. Seventeen of these patients had orthodox medical care for their wounds before developing tetanus. While some of the patients had received antibiotics and/or tetanus toxoid, no patient received antitetanus serum despite the fact that most of them had no previous immunization against tetanus. All the 3 victims of road traffic accidents were given tetanus toxoid but none of the 6 patients with chronic suppurative otitis media had any form of tetanus prophylaxis. The findings highlight the adverse consequences of failure to adhere to basic guidelines for management of the tetanus-prone wound.

Adult↗