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Biomedical subjects

J B George

Publications and source records attributed to J B George.

6 recordsLinked to original sources
PubMed1999

Toxicity of neem seed oil (Azadiracta indica) against the larvae of amblyomma variegatum a three-host tick in cattle.

The in vitro toxicity of neem seed oil (Azadiracta indica, family: Meliaceae, 'Dogon yaro' in Hausa -language) was tested against the larvae of a three-host tick, Amblyomma variegatum (family: Ixodidae or hard tick) parasitic to cattle commonly found in Nigeria. Undiluted neem oil (100% concentration) was found to kill all (100% mortality) the larvae after 48 h. The toxicity was concentration and time dependent.

Animals↗
PubMed1995

Yeast artificial chromosome contigs reveal that distal variable-region genes reside at least 3 megabases from the joining regions in the murine immunoglobulin kappa locus.

The immunoglobulin kappa gene locus encodes 95% of the light chains of murine antibody molecules and is thought to contain up to 300 variable (V kappa)-region genes generally considered to comprise 20 families. To delineate the locus we have isolated 29 yeast artificial chromosome genomic clones that form two contigs, span > 3.5 megabases, and contain two known non-immunoglobulin kappa markers. Using PCR primers specific for 19 V kappa gene families and Southern analysis, we have refined the genetically defined order of these V kappa gene families. Of these, V kappa 2 maps at least 3.0 Mb from the joining (J kappa) region and appears to be the most distal V kappa gene segment.

Animals↗
PubMed1992

Louse and mite infestation in domestic animals in northern Nigeria.

Records of domestic animals brought to the Veterinary Entomology Laboratory for diagnosis of suspected lice and mite infestation over a 10 year period were analysed. From a total of 794 suspected cases, 137 (17.3%) and 247 (31.1%) were positive for lice and mange mites respectively. The most common lice species recorded were Linognathus vituli (66.7%) on cattle, L. ovillus (83.3%) on sheep, Haematopinus suis (100%) on pigs and Menacanthus stramineus (54.5%) on poultry. Other lice species recorded included Haematopinus bovis and Solenopotes capillatus on cattle, Damalinia ovis on sheep, Linognathus stenopsis and Menacanthus stramineus on goats, Goniocotes sp. on a horse, Linognathus setosus and Menacanthus stramineus on dogs, Goniodes gigas, Lipeurus caponis, Menopon gallinae and Chelopistes meleagrides on poultry. The most common mite species were Demodex folliculorum on cattle (96.9%) and on dogs (80.8%), Sarcoptes scabiei on pigs (100%) and Notoedres cati (80.3%) on rabbits. Other mite species included Psoroptes communis, Cheyletiella parasitivorax, Ornithonyssus gallinae and Dermanyssus gallinae.

Animals↗
PubMed1992

Genetics: challenges for nursing education.

Rapid development of new knowledge in genetics has not been matched by increased inclusion of genetics content in nursing education or nursing research. Genetics is viewed as tangential to nursing, a useful but not necessary component of nursing knowledge. A paradigm shift to a view of genetics as a science basic to the practice of nursing is proposed. Methods to achieve this shift are presented.

Education, Nursing, Baccalaureate↗
PubMed1985

Fiber number, area, and composition of mouse soleus muscle following enlargement.

Muscle fiber number, cross-sectional area, and composition were studied in response to enlargement produced by synergistic ablation in the mouse soleus muscle. The effect of the location of a histological section on the number of fibers that appear in the section was also studied using the mouse soleus muscle. Enlargement was produced in the soleus muscle of 15 male and 15 female mice by ablation of the ipsilateral gastrocnemius muscle. Fiber counts, using the nitric acid digestion method, revealed no difference between control and enlarged muscles in male and female mice. Mean fiber area, determined by planimetry, was 49.1 and 34.5% greater following enlargement in male and female mice, respectively. Increase in muscle weight could be totally accounted for by the increase in fiber area following enlargement. A transformation of type II to type I fibers occurred following enlargement for both sexes. Counts of fibers from histological sections revealed that there was a progressive decrease in the fiber number as the section was moved from the belly to the distal end of the muscle. The results of these studies indicate that muscle enlargement in the mouse soleus muscle is due to hypertrophy of the existing muscle fibers.

Animals↗