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Biomedical subjects

J B Hourihane

Publications and source records attributed to J B Hourihane.

9 recordsLinked to original sources
PubMed1994

Reasons underlying negative mammography in patients with palpable breast cancer.

It is well recognized that a negative mammogram report does not exclude the presence of breast carcinoma. This study examines the accuracy of mammography in patients with palpable breast cancer. In particular, the study evaluates the reasons underlying negative mammography in breast cancer. All patients with Paget's disease, carcinoma in situ lesions or lesions infiltrating skin were excluded. A total of 291 patients presenting with palpable breast carcinoma underwent mammography prior to biopsy. False negative reports occurred in 16.5% (48). The sensitivity of mammography increased with age, from 70% (14/20) in 31-40-year-olds to 91% (113/124) in women over 60 years. Retrospective review of false negative mammograms showed that 30% of these were deemed normal while 20% were obvious oversights. The remaining 50% showed subtle radiographic abnormalities, consistent with but not diagnostic of malignancy.

Adult↗
PubMed1994

Pain and increased mammographic density in women receiving hormone replacement therapy: a prospective study.

OBJECTIVE: A prospective study was designed to evaluate the effects of hormone replacement therapy on mammographic density in postmenopausal women. The possible association of breast pain with increased mammographic density was evaluated. SUBJECTS AND METHODS: Thirty-three postmenopausal women undergoing hormone replacement therapy for a mean of 11 months had mammography before and after commencing treatment. As a control, 31 postmenopausal women who never had hormone therapy also had baseline and follow-up mammograms after a mean of 13 months. Subjects were asked whether breast pain, which they graded as mild, moderate, or severe, had developed since their entry into the study. Baseline and follow-up mammograms were assessed objectively and subjectively for interval changes in density. The presence of breast pain was correlated with changes in density on the mammograms. RESULTS: A subjective increase in mammographic density was seen in nine (27%) of the women taking hormones and in none of the control subjects (p = .002). Changes were focal in four, multifocal in four, and diffuse in one. An increase in density was seen with all types of treatment used, and was noted as early as 4 months after the start of treatment. Seven (78%) of nine patients with mammographic changes had breast pain, which they classed as moderate or severe, that had developed since the start of treatment. In five patients with mild or moderate breast pain, an increase in density was not shown on mammograms. Of the 21 women taking hormones who did not have breast pain, increased density on follow-up mammograms was shown in only two (p = .004). None of the patients in the control group had breast pain. CONCLUSION: Focal, multifocal, or diffuse mammographic increases in density occur in a significant percentage of women undergoing hormone replacement therapy. A large proportion of these women have breast pain. Increased mammographic density appears to be associated with breast pain in women receiving hormones. This has implications for mammography in women receiving hormone replacement therapy.

Breast↗
PubMed1992

Mammographic needle localisation of impalpable breast lesions.

Refinements in mammography have led to an increased number of needle localised breast biopsies for impalpable breast lesions. This paper review 139 needle guided biopsies from June 1986 to December 1990 in 132 patients. Forty four patients (32%) biopsied had malignant lesions the vast majority (91%) of which were reported as either non-invasive or invasive less than 2 cm in diameter. Fourteen patients in this group had ductal carcinoma in-situ. When compared with 100 consecutive palpable breast carcinomas during the same period, needle localised biopsies had a higher proportion of non-invasive lesions and fewer were associated with lymph node involvement. Needle guided breast biopsy detects carcinoma at an earlier stage and may reduce morbidity and mortality from breast cancer.

Biopsy, Needle↗
PubMed1989

A pitfall in the diagnosis of lobar collapse.

In patients who have a superior accessory fissure, collapse of the upper or middle lobe may be overlooked as the anomalous fissure may be mistaken for the horizontal fissure on the postero-anterior view. Five cases are presented.

Aged↗
PubMed1987

Simplified peripheral arteriography.

Demonstration of both iliofemoral arteries and their peripheral run-off is usually performed either by the translumbar approach, or by placing a pigtail catheter at the aortic bifurcation. A modified version of the old retrograde pressure method, simply using a cannula in one femoral artery, is described. There was considerable saving in materials, personnel and time. This method may once again be the method of choice in a busy radiology department.

Aged↗
PubMed1981

Ultrasound guided percutaneous abdominal abscess drainage.

Traditional management of abdominal abscess is according to classical surgical methods. Catheter or needle drainage of these abscesses, using ultrasound both as an imaging modality and as a monitor of technique, offers a safe and rapid method of drainage of all types of abdominal abscess and eliminates surgery in many patients. Eleven abdominal and retroperitoneal abscesses were satisfactorily drained under ultrasound control in ten patients. No abscess recurred, but in three patients subsequent surgery was performed, in one because the abscess was multiloculated, and in the other two to exclude underlying malignancy.

Abdomen↗