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Biomedical subjects

J B Love

Publications and source records attributed to J B Love.

9 recordsLinked to original sources

Do cardiorespiratory frequencies show entrainment with hopping in the tammar wallaby?

Breathing, heart and gait frequencies, tidal volume, cardiac output, and rates of oxygen consumption were measured in tammar wallabies (Macropus eugenii Desmarest) hopping on a treadmill. At speeds greater than 1.6 ms-1 the rate of metabolic power consumption was independent of hopping speeds. Blood lactate levels within the speed range where VO2 was independent of speed showed a mean increase of 4.8 mmol l-1. During bipedal hopping, the frequencies of breathing and limb movement are phase-locked in the ratio of 1:1. Inspiration begins as the animal leaves the ground and may be a passive process driven by a visceral piston. A relatively large central tendon in the diaphragm may correlate this function. Unlike breathing frequencies, cardiac frequencies show no entrainment with hopping. The site of dissipation of the presumed large arterial pressure excursion is unknown.

Animals↗

Adult epiglottitis. Is there a role for the fiberoptic bronchoscope?

The "cherry red" laryngoscopic appearance of adult epiglottitis, as visualized through a fiberscope, is reproduced. The possible role of the fiberoptic bronchoscope, both as a diagnostic aid and as a means of facilitating endotracheal intubation, in this condition, is discussed.

Bronchoscopes↗

Use of a microprocessor in the control of malignant hypertension with sodium nitroprusside.

In a malignant hypertensive, steady control of blood pressure at a pre-determined level has been achieved with the continuous intravenous infusion of sodium nitroprusside. A microprocessor was programmed to assess the patient's blood pressure and adjust the rate of nitroprusside infusion so that a mean pressure of 106 mmHg was achieved. Brief interruption of the nitroprusside infusion allowed the effectiveness of changes in oral therapy to be evaluated. Thiocyanate concentrations were measured throughout as an index of potential nitroprusside toxicity. After six days, blood pressure control was maintained with oral therapy alone and papilloedema had almost resolved.

Adult↗