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Biomedical subjects

J B Lyon

Publications and source records attributed to J B Lyon.

16 recordsLinked to original sources
PubMed1987

Careful surgical technique can reduce infectious morbidity after cesarean section.

A total of 635 consecutive cesarean sections performed in private practices during the past 20 years are reviewed. In the course of this 20 year period, we have tried to alter gradually our surgical technique used for this procedure to conform to the principles of surgery developed by Halsted. The study is divided into three periods of time to examine the results of changes in technique. With the use of the standard definition of febrile morbidity (temperature of greater than or equal to 100.4 degrees F during any two 24-hour periods after the first postoperative 24 hours) the postoperative morbidity rate was 15% during 1967 to 1973, 5.4% during 1974 to 1979, and 0.7% during the period 1980 through 1986. Prophylactic antibiotics were used with decreasing frequency. It was clear that the reduction in morbidity was the result of the modifications in surgical technique.

Anti-Bacterial Agents↗
PubMed1981

The effect of condom use on squamous cell cervical intraepithelial neoplasia.

Between January 1, 1968, and July 1, 1980, 377 of a total 412 patients with biopsy-proven cervical intraepithelial neoplasia (CIN) were seen in the private office of the authors and followed for more than 6 months after biopsy and the start of treatment. Thirty-five patients were lost to follow-up. Ninety-one were treated primarily by hysterectomy. The 286 patients in whom childbearing function was to be preserved were instructed, as soon as the diagnosis of CIN was confirmed, to use a mechanical barrier (the condom) throughout intercourse. In addition to the use of the condom, 40 of the 286 underwent surgical conization and 107 underwent cryosurgery. All of these 147 patients eventually showed cytologic and colposcopic regression of the disease. One hundred and thirty-nine patients were treated with the condom alone. One hundred and thirty-six of the 139 showed complete regression of the disease. Eighteen (6.2%) of the 286 patients had late recurrences of the disease; 12 of these experienced regression again with the resumption of the use of the condom. No patients showed progression of the disease while using the condom. All grades of CIN proved to be reversible. It is recommended that a mechanical barrier at intercourse be added to any program for conservative treatment of CIN.

Adult↗
PubMed1976

A new look at pelvic relaxation.

The concept is presented that most cystoceles and/or urethroceles result from insolated defects in the connective tissue supports of the anterior quadrant of the pelvis. Four areas in which defects have been found to occur are identified. Sixty patients are presented who were found to have isolated defects in the endopelvic fascia at the lateral sidewall of the pelvis with significant cystourethroceles and stress urinary incontinence. The surgical treatment consisted only of a direct approach to and closure of the isolated defect. The operative results at 3 to 48 months were excellent in 91.7 per cent, improved in 5 per cent, and failed in 3.3 per cent. Discussion is offered of the possibility of the study of the pelvic floor from the viewpoint of a mechanical engineer.

Female↗
PubMed1976

Decreasing postpartum sexual abstinence time.

Postpartum sexual abstinence time can be safely shortened for most patients when episiotomy repair is done meticulously with fine PGA suture on small needles. The time preferred by patients for resumption of intercourse seems to be between the second and third postpartum week. We have seen no ill effects from this, and we feel that sexual intercourse at these early dates does not influence the healing of the episiotomy in any way.

Episiotomy↗
PubMed1970

Bites and stings.

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Bites and Stings↗
PubMed1967

Phosphorylase b kinase inheritance in mice.

The gene for phosphoryl ase b kinase, a skeletal muscle enzyme, has been located on the X chromo some of mice. The inheritance of the enzyme through two generations from original matings between one inbred strain of mice, the I, which lacks the enzyme, and another strain, the C(57,) follows the classical Mendelian pattern.

Adenine Nucleotides↗