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Biomedical subjects

J B Mackay

Publications and source records attributed to J B Mackay.

11 recordsLinked to original sources

Mucociliary transport and ultrastructural abnormalities in Polynesian bronchiectasis.

Ciliated bronchial or nasal epithelium from 20 Polynesian bronchiectatic patients was examined in an electron microscope. In all patients there was a partial or complete loss of dynein arms. Also, in many patients other ciliary abnormalities were present with a high proportion, often over 25%, of cilia affected. This contrasts with a control group where ciliary abnormalities were infrequent. Mucociliary clearance, measured by imaging 99mTc sulfide dust with a gamma camera, was either absent or markedly reduced in these bronchiectatic patients.

Bronchi↗

Drug resistant tuberculosis in New Zealand.

Strains of M. tuberculosis resistant to one or more of the antituberculous drugs have not been common in New Zealand in the past. There is however, a high incidence of drug resistant tuberculosis in Western Samoa, 50 percent of cultures tested showing drug resistance and half of these are resistant to two or more drugs. A change from the usual initial treatment is suggested for Samoan patients with tuberculosis in New Zealand.

Adolescent↗