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Biomedical subjects

J B Stewart

Publications and source records attributed to J B Stewart.

At least 19 recordsLinked to original sources
PubMed1998

Security and confidentiality in an electronic medical record.

The maintenance of privacy and confidentially must remain a core principle of the interaction between patients and medical staff. Traditionally, the single paper copy of the medical history has been treated with systematic handling, careful tracking, and respect for the integrity and confidentiality of the contents. The widespread availability of computerized information requires that these principles be maintained in the electronic environment. Security measures should protect sensitive data without hindering medical practice. At Mayo, we have established data security policies and standards for the handling of all electronic information. Dissemination and communication of these standards and guidelines are an ongoing challenge. Technical maneuvers can be employed to protect data integrity, identify users, and monitor compliance. Personnel policies must be updated to reflect the responsibilities and liabilities of the electronic environment. Practice efficiencies and access to clinical data must be balanced by individual responsibility and accountability for privileged patient information.

Computer Security↗
PubMed1996

The "shutter flap" for large defects of the forehead.

Acquired defects involving exposed bone in the central forehead can be challenging to reconstruct. We present a simple technique in which two superiorly based flaps of galea frontalis and skin are transposed medially, like the shutter of a camera. Full-thickness grafts are used to close the donor site. This is a remarkably easy way to close some very large forehead wounds.

Aged↗
PubMed1994

Neuroleptic medication for dystonia. Reciprocal relationship between effects on motor function and mood.

BACKGROUND: The presence of dysphoric symptoms associated with neuroleptic medication is commonly reported. METHOD: Neuroleptic treatment of a segmental dystonia resulted in a disabling depressive illness, which when treated with antidepressants led to the return of the involuntary movements. RESULTS: The use of several different antidepressants and neuroleptics confirmed the association between drugs and symptoms. Genetic studies excluded "poor metaboliser status" as a reason for the patient's sensitivity to these drugs. CONCLUSIONS: The case illustrates a delicate imbalance between dose of neuroleptic medication and depressive symptoms. We should be aware of the possibility of mood changes in patients treated with neuroleptics for a variety of conditions.

Adult↗
PubMed1992

Tissue sparing repair. A new approach to shorten excisional lines.

Tissue sparing repair uses primary closure to make a circular or irregular defect into a line. The resultant closure ratio is 1.5:1 without a dog-ear defect for circular closures. Irregular defects will have different closure ratios. Two new suture techniques are used: 1) the horizontal oblique dermal suture, which approximates tissue without undermining and with minimal epidermal wound edge tension; and 2) the apex cutaneous suture, which repairs most dog-ear defects with a suture. Tissue sparing repair may be a useful addition to primary wound closure.

Basal Cell Carcinoma↗
PubMed1990

Rectal polyposis in tuberous sclerosis.

Microhamartomatous rectal polyps are described in 11 out of 15 patients with tuberous sclerosis (TS). These readily identifiable polyps are of no clinical significance but their prevalence and unique nature rank them as of equal importance to other better known markers of TS such as the facial angiofibromata (adenoma sebaceum).

Adolescent↗
PubMed1988

Double-blind comparison of olsalazine and sulphasalazine in active ulcerative colitis.

Fifty-six patients with ulcerative colitis of mild to moderate severity were entered into a randomized, double-dummy comparison of sulphasalazine, 3 g/day, with olsalazine, 3 g/day. Patients were assessed clinically, and by sigmoidoscopy and biopsy, on entry and at 5 weeks. Both agents produced a similar reduction in stool frequency and in the passage of blood and mucus. Improvements in sigmoidoscopic and histological appearances of the rectal mucosa were observed to a similar extent in both groups of patients. Two patients treated with olsalazine were withdrawn because of increased diarrhoea attributable to the medication. Two patients given sulphasalazine for the first time developed a skin rash. Other side-effects seen during the trial were mild. In this small short-term study, oral olsalazine appeared to be as effective as sulphasalazine in the treatment of mild to moderate ulcerative colitis.

Adult↗
PubMed1988

Cytotoxic, fungicidal nucleosides from blue green algae belonging to the Scytonemataceae.

Tubercidin, toyocamycin, and the corresponding 5'-alpha-D-glucopyranose derivatives of the nucleosides are frequently responsible for much of the cytotoxicity and antimycotic activity associated with extracts of cultured cyanophytes belonging to the family Scytonemataceae. The 5'-alpha-D-glucopyranoses of tubercidin and toyocamycin, for example, are the major cytotoxic and fungicidal nucleosides in Fijian Plectonema radiosum and Hawaiian Tolypothrix tenuis, respectively.

Antifungal Agents↗
PubMed1982

Gas-liquid chromatography of positive blood cultures for rapid presumptive diagnosis of anaerobic bacteremia.

Gas-liquid chromatographic analysis of volatile fatty acid patterns was performed when growth was initially detected in 87 positive blood cultures. Isovaleric acid, butyric acid, or both were found in 39 of 43 (90%) blood cultures that contained anaerobes but were absent in all 44 cultures that contained facultatively anaerobic or aerobic bacteria. The detection of isovaleric acid indicated the presence of Bacteroides fragilis, as this acid was found in 88% of unimicrobial and 75% of polymicrobial bacteremias due to B. fragilis. Butyric acid was detected most often in blood cultures which grew Fusobacterium spp. (three of three), Clostridium spp. (six of seven), or both (three of four).

Bacteroides Infections↗
PubMed1980

Intestinal amoebiasis for 36 years.

A case is reported of amoebic dysentery in a former soldier who had symptoms of Entamoeba histolytica infection for 36 years. It emphasizes the need for careful search for parasites in the stools of any patient with bowel symptoms because the consequences of wrong diagnosis are potentially catastrophic.

Chronic Disease↗