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J B dos Reis-Filho

Publications and source records attributed to J B dos Reis-Filho.

13 recordsLinked to original sources
PubMed1997

[Subarachnoidal hemorrhage with cranial tomography without bleeding signals].

UNLABELLED: We observed 23 patients with clinical hypothesis of subarachnoidal hemorrhage (SAH) having cranial tomography (CT) without bleeding signals. The final diagnosis of SAH was made upon the cerebrospinal fluid (CSF) results. Twenty cases were submitted to brain angiography. They were focused under the clinical classification of Hunt & Hess. The main results were 1) 1/3 of patients had interval time between 24 and 48 hours after ictus and before CT and CSF making; this was the most sensitive CT time; 2) 55% of patients with brain angiography had aneurysm predominantly in the carotid and anterior cerebral artery territory; 3) the dominant clinical degree was Hunt & Hess I e II. CONCLUSION: the results demonstrate the need of CSF test in case of SAH clinical diagnosis with CT showing no bleeding signals.

Aged↗
PubMed1995

[CSF total proteins in the prognosis of patients with subarachnoid hemorrhage].

The main purpose of this study was to verify the value of CSF total proteins level on the prognosis of subarachnoid hemorrhage. In order of this, samples of 254 patients with diagnosis of intracranial bleeding were analyzed, with special attention to the rate of CSF total proteins. Statistical tests for evaluation of the results have been accomplished, revealing a close relationship between the total proteins rates increase and death in patients with subarachnoid hemorrhage, independent of sex and age. The limit score of total proteins level for survive was 3000 mg/100 ml (nephelometric method).

Adolescent↗
PubMed1983

[Function of purification drainage of the central nervous system through the cerebrospinal fluid].

It has long been known that the cerebrospinal fluid can not be the nervous system lymph, and Mestrezat, in his authoritative book of the year 1912, demonstrated it plainly. Davson has undertaken this subject and suggested the hypothesis of a sink action of cerebrospinal fluid, allowing a slow leakage of solutes from nervous tissue extracellular space. In order to test this hypothesis, Oldendorf and Davson performed a series of animal experiments and they demonstrated that there was leakage of the solute into cerebrospinal fluid. Based on the idea of this sink action of cerebrospinal fluid, some possible physiological implications were considered such as the mechanism of origin of the ventricle-subarachnoid cerebrospinal fluid protein gradient; the mechanism of protection of the central nervous system against the harmful substances of the blood stream; and the homeostatic mechanism whereby the concentration of some ions of the fluid remains constant. Also, it is considered the possibility of a sink action of cerebrospinal fluid in the resolution of brain edema in water intoxication and other types of central nervous system edema.

Animals↗
PubMed1983

[Ventriculo-lumbar gradient of concentration of total cerebrospinal fluid proteins: 1 - mechanisms of origin].

In normal conditions there is a concentration gradient of proteins along the neuraxis. From a low level in the ventricles, ranging from 5 to 15 mg/10C ml, to an intermediate level in the cisterna magna, the protein content reaches its highest level in the lumbar sac, 12 to 44 mg/100 ml. Several mechanisms were considered to elucidate the origin of this gradient but many investigators think that the progressive increase of the protein concentration is best explained by the transfer of proteins from serum to the cerebrospinal fluid due to the relatively raised permeability of blood-cerebrospinal fluid barrier in the spinal subarachnoid space. This paper presents a study of the protein concentrations in cisternal and lumbar cerebrospinal fluid samples of patients with neurocysticercosis in activity. The 11 patients of the first group had free subarachnoid space communication between the cisterna magna and the lumbar sac; the 6 patients of the second group had a complete block of the subarachnoid space between these two levels. In every cerebrospinal fluid specimen the quantitative complement fixation test for cysticercus was performed and the titer determined in order to make an assessment of the central nervous system humoral immune response. The analysis of the data of this investigation shows that the concentration gradient of proteins is evident in the cerebrospinal fluid of patients with patency of the spinal subarachnoid space, and the ratio of concentrations of protein contents in simultaneous cisternal and lumbar samples was similar to that one observed in normal individuals. This gradient is also detected when the intensity of the humoral immune response is determined by quantitative complement fixation test for cysticercus in simultaneous cisternal and lumbar specimens. After the onset of spinal subarachnoid block, the confront of the results of the tests in cerebrospinal fluid samples, obtained before and after the blockage, shows a large increase both in the total protein content as well as the intensity of the humoral immune response, in the lumbar level. The similar increases both in protein concentration and titer of cysticercus complement fixation test in the lumbar fluid, in comparison with the cisternal fluid, in patients with patent spinal subarachnoid space, and the large simultaneous and similar increases in both protein content and titer of the cysticercus complement fixation test in the lumbar fluid of patients with spinal subarachnoid block are in disagreement with the usual explanation of the origin mechanisms of the gradient.(ABSTRACT TRUNCATED AT 400 WORDS)

Antibody Formation↗
PubMed1983

[Ventriculo-lumbar gradient of concentration of total cerebrospinal fluid proteins: 2.- Influence of CSF drainage by ventriculoatrial shunt].

On a previous paper, based upon the data obtained from comparative studies of cerebrospinal fluid samples of two groups of patients with neurocysticercosis in activity, one with patency, the other one with blockage of the spinal subarachnoid space, evidence was presented that the concentration gradient of proteins along the neuraxis was the consequence of the escape of water from cerebrospinal fluid. The second paper is a continuance of that one. The material for this survey consisted of the clinical records of 11 patients with neurocysticercosis who during the course of the disease presented severe intracranial hypertension which required ventriculoatrial shunt as an emergency operation in order to allow survival. After surgery, it was observed a marked improvement in the clinical picture. Later, it was noticed a large increase in the protein content of the spinal fluid of the majority of the patients, as compared with the results verified prior to surgery. However, in these spinal fluid samples the increase in protein content was observed without a simultaneous rise in cell count, suggesting an improvement in the inflammatory condition. It seems very likely that this large elevation of the protein content in the subarachnoid fluid is the consequence of a reduction in the spinal fluid flow rate due to the ventricle-venous shunt.(ABSTRACT TRUNCATED AT 250 WORDS)

Central Nervous System Diseases↗
PubMed1983

[Incidence of neurosyphilis and incidence of its clinical forms 1962-1981].

After 1950 it was observed an increase in the incidence of syphilis in the general population and this fact determined an investigation in order to evaluate the possible repercussion of this occurrence on the central nervous system, as an after effect of the elevated incidence. However, in this first study it was verified that there was a progressive and marked decrease of the neurosyphilis incidence in the 1936-1964 period, and that the frequency of meningovascular forms of the disease had increased lately in regard to the parenchymatous forms. The aim of the present work has been the continuation of this study after so many years. The material for this survey consisted of the clinical records of 148 patients picked out from 34.430 cases seen at the Neurological Department of Escola Paulista de Medicina (São Paulo, Brasil), during the 1962-1981 period, i.e., on twenty consecutive years. The results of this complementary investigation have shown instead that the incidence of neurosyphilis remained steady, changing very little every year, with an incidence at the rate of about 1:200. On the other hand, the frequency of the clinical forms of neurosyphilis changed very much. The usual forms such as general paresis and tabes are now scant and the observation of the uncommon forms, seldom seen in the past, is now progressively increasing through the years, so that they are the preponderant clinical forms today.

Brazil↗
PubMed1980

[Semiologic value of erythrocyte macrophages in the cerebrospinal fluid].

An investigation was made in the cerebrospinal fluid of 82 patients who had bleeding into the subarachnoid space or other neurologic disorders in order to study the macrophages. The ages of these patients ranged from 24 hours to 80 years. It was verified that the macrophages with red blood cell could be demonstrated from 24 hours until 30 days after the onset of the bleeding. The macrophages with hemosiderin were observed after the 6th day after the onset of the bleeding, and they could be seen in some cases after 70 days. It was discussed the assertion that the simultaneous presence of red blood cell and hemosiderin in the cytoplasm always indicates repeated hemorrhage. In a 24-hour-old newborn baby with bleeding in the subarachnoid space it was found macrophage with hemosiderin. This anomalous finding pointed out to hemorrhage during the intrauterine life.

Adolescent↗
PubMedDate not supplied

Cerebrospinal fluid syndromes in HIV-positive patients with acute consciousness compromise.

We reviewed the cerebrospinal fluid (CSF) syndromes of 100 consecutive HIV-positive patients presenting acute consciousness compromise in emergency rooms, and correlated them with clinical data. The most frequent CSF syndromes were: absolute protein-cytological dissociation (21), viral (19), neurocryptococcosis (7), relative protein-cytological dissociation (6) and septic (4), moderate hypoglycorrachia (4), severe hypoglycorrachia (4) and hydroelectrolytic disturbance (3). One fifth of the patients had CSF syndromes considered sufficient for diagnosis or an immediate clinical decision. The most common clinical data were infective and neurological. There was little correlation between the clinical data and the CSF syndromes. We conclude that in HIV-positive individuals presenting acute consciousness disturbances there are frequently non-specific results in the CSF analysis that must be weighed against a detailed history and thorough physical examination. Taking this into account, in about one fifth of cases the CSF analysis can offer useful information for treatment.

AIDS Dementia Complex↗
PubMedDate not supplied

[Comparison between CSF samples from AIDS and non AIDS patients with neurocryptococcosis].

Neurocryptococcosis was a rare nervous system infection. With the rising number of patients with AIDS it became a very frequent disease. This infection is supposed to infect patients with some kind of immunodeficiency and the CSF alterations often simulate tuberculous meningitis. The purpose of this research was to compare the CSF changes in AIDS and non-AIDS patients with meningoencephalitis caused by Cr. neoformans. There were analysed 41 CSF samples from non-AIDS patients with neurocryptococcosis and 23 CSF samples from AIDS patients with neurocryptococcosis. The results of this research allowed to conclude that the inflammatory changes in the CSF from AIDS patients showed a lower intensity compared to those non-AIDS patients. These results showed as well, that the CSF samples from non-AIDS patients always revealed some changes besides the yeast cells. In some samples of AIDS patients, however the unique change was the presence of the yeast. It was demonstrated also, that the presence of Cr. neoformans in CSF, not accompanied by any other change, may suggest that is a patient with AIDS. In non-AIDS patients CSF alterations often simulates tuberculous meningitis. However these alterations were rare in AIDS patients. The yeast cells were more numerous in CSF samples from AIDS patients than in those from non-AIDS patients.

Acquired Immunodeficiency Syndrome↗