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Biomedical subjects

J Bagley

Publications and source records attributed to J Bagley.

23 records · Page 2Linked to original sources

Assessment of bullet injuries in the neck (a salutory lesson).

Bullet injuries in the neck are fortunately rare in England and Wales, although their incidence is increasing. Clinical assessment of the extent of the injury and the decision whether or not to explore the neck in the absence of obvious major visceral or vascular damage can be difficult. We report a case where a potentially fatal injury was not suggested by the patient's clinical condition and we recommend prompt exploration of bullet wounds in the neck whenever there is a possibility of vascular damage.

Adult↗

The use of prothrombin activating snake venoms to measure human prethrombin 2: absence of prethrombin 2 in serum.

The activation of the prothrombin intermediate, Prethrombin 2, has been studied in order to establish test systems that would enable identification of Prethrombin 2 in serum and Factor IX concentrates. While activation of Prethrombin 2 by Taipan Snake Venom (TSV) was slow and incomplete, inclusion of approximately molar amounts of prothrombin fragments F1 or F1.2 markedly enhanced the amount of thrombin formed by TSV. This effect could also be obtained by the inclusion of serum. Neither normal serum nor Factor V deficient serum contain any identifiable Prethrombin 2. On the other hand substantial amounts of Prethrombin 2 are present in Factor IX concentrates used for the treatment of Christmas Disease (Hemophilia B).

Chromatography, DEAE-Cellulose↗