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Biomedical subjects

J Baltsch

Publications and source records attributed to J Baltsch.

5 recordsLinked to original sources

[Different approaches to long-term O2 therapy (LTOT) in patients using intermittent positive pressure ventilation].

BACKGROUND: Until now there is no conclusion about a distinguished long-term O2 therapy in patients using IPPV. PATIENTS AND METHODS: 24 patients (6 women, 18 men, mean age 60 years, mean length of IPPV 15.6 months, mean length of long-term O2 therapy 16.7 months) with IPPV and long-term O2 therapy were studied by the topical and the past dose and the length of long-term O2 therapy. RESULTS: 1. Thirteen patients had the highest need for oxygen under strain with same need under IPPV and daytime. 2. The distribution among the others was different, 3 patients showed an elevated need for oxygen from IPPV to day-time to activity, 3 needed oxygen only under strain. 3. Changing the length was necessary in 4 patients. 4. The individual dose was changed in the course in 18 patients, reduced in 4, raised in 6 and both in 8 patients. CONCLUSION: 1. A distinguished long-term O2 therapy with testing the need in rest, under IPPV and in activity is convenient. 2. Regular controls are necessary because of the individual changings.

Female↗

[Expanded palliative indications for transtracheal oxygen administration].

Transtracheal oxygen therapy (TTOT) is applied particularly to patients with chronic obstructive pulmonary disease. We treated four patients in a preterminal stage of their disease, the primary diagnoses being pulmonary fibrosis and bronchoalveolic carcinoma. Oxygen administered by nasal delivery devices had been inefficient in all patients. TTOT reduced dyspnoea, improved exercise tolerance and reduced hospital stay. We conclude that TTOT has a potential for being medically beneficial in a preterminal stage of pulmonary fibrosis and carcinoma.

Aged↗

[Detection of bronchial hyperreactivity using the 1-step histamine test].

An attempt was made to establish whether patients with, and those without, bronchial hyperreactivity can be reliably differentiated on the basis of a single-step histamine provocation test. Thirty-five asymptomatic persons (7 normal subjects, 13 patients with a history of coughing and oppressive sensation, and 13 patients with bronchial asthma) inhaled 10 breaths of a 5% histamine solution after a trial run with physiological NaCl solution. SGaw was determined in a volume constant body plethysmograph. The median dose of histamine was 0.51 mg, the sGaw median after inhalation was 0.37 kPa-1s-1. Between the values for sGaw prior to and following inhalation, and the histamine dose, a linear dose response curve was plotted, from which PD25sGaw was interpolated. On the basis of PD25sGaw, patients with bronchial hyperreactivity and normal subjects could be differentiated. At a PD25sGaw threshold value of 0.27 mg, the sensitivity is 0.85 and the specificity 0.86. Thus, the results obtained with single-step histamine provocation are comparable with those obtained with the conventional provocation methods involving increasing concentrations of histamine, and with those of the methacholine single-step provocation challenge.

Airway Resistance↗