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Biomedical subjects

J Baragan

Publications and source records attributed to J Baragan.

At least 37 records · Page 2Linked to original sources
PubMed1976

[Correlation between the angiographic appearance and the left intraventricular gradient in obstructive myocardiopathy. Apropos of 42 cases].

42 patients who were given the diagnosis of obstructive cardiomyopathy (OCM) on the basis of a basal left intraventricular systolic gradient equal to or in excess of 20 mmHg were divided into two groups, according to the angiocardiographic appearances (in the right anterior oblique projection) of the left ventricular cavity during systole. In 20 cases the appearances were those of a typical obstructive cardiomyopathy. In the other 22, despite the presence of a fairly large left intraventricular gradient, the appearances on angiocardiography were closest to those described for the non-obstructive cardiomyopathies with diffuse myocardial hypertrophy. These two groups were compared in the quest for a difference between the clinical, radiological, electrocardiographic, phonomechanographic, and haemodynamic picture on the one hand, and the appearances at angiography on the other. These two groups can only be separated by the mean value of the left intraventricular systolic gradient established under basal conditions; this is greater when the angiographic picture is less characteristic. However, the value of this gradient is shown by the positive correlation between the figure for the gradient and that for the left ventricular ejection time, as determined from external phonomecanographic measurements and from the catheter on the left side. This determination confirms the existance of obstruction to the outflow and the diagnosis of obstructive cardiomyopathy, even when the angiographic appearances are not typical.

Adolescent↗
PubMed1976

[Long term results of surgical treatment of obstructive myocardiopathy by intervention on the interventricular septum].

An analysis of the results of septal myotomy or myectomy in 26 adults with obstructive cardiomyopathy (OCM) with a mean follow-up period of more than 5 years lead to the conclusion that this treatment brings about, at the price of a mortality rate of about 10%, a sustained improvement in function, a reliable correction of the left ventricular gradient, and an improved long term survival rate by comparison with the rate among patients treated medically.

Adolescent↗
PubMed1976

[Spontaneous development of obstructive myocardiopathies].

49 cases of obstructive cardiomyopathy (37 of the sporadic type, 12 of the familial type), confirmed by phonomechanocardiographic, haemodynamic and/or angiographic investigation and followed up for more than 5 years (mean 7.5 years) without surgical intervention, form the basis of a study on the natural history of this condition. There were 19 deaths (39%), of which 7 were of the familial type (58%) and 12 of the sporadic type (32%). The actuarial survival curves, which were commenced at the time or the first clinical symptom or the date of the first hospitalisation, show that approximately one patient in two dies at or about the age of 40. In 6 cases, death occurred in patients who were greatly improved by medical treatment to the extent of remaining symptomfree up to the time of death. No factors could be found in the initial investigation (phonomechanocardiographic electrocardiographic, radiographic, haemodynamic and angiographic examination (phonomechanocardiographic, electrocardiographic, between the patients still alive and those who had died; each paramater studies had mean values which overlapped in the two groups. Only the age at which the first clinical feature appeared separated the two groups: those patients who died had their first symptom or sign of disordered function at a much younger average age (15.9 years) than the survivors (25 years). This study has confirmed the very serious nature of obstructive cardiomyopathy, especially the familial types, and those with a low age of onset. It emphasises the extreme difficulty in arriving at a prognosis in this condition.

Adolescent↗
PubMed1975

[Telesystolic mitral insufficiency with systolic click, mitral valve prolapse, and hypertrophic obstructive myocardiopathy].

There are several causes of the syndrome of "Late systolic murmur and mid-systolic click" due to mitral incompetence with ballooning of the valve, and, as numerous recent publications have shown, amongst them must be included abnormalities of left ventricular contraction. Seven cases have been studied by phonomechanocardiographic, cineangiographic, and haemodynamic methods, and analysis of the findings has shown that the abnormalities of contraction may be due to a cardiomyopathy, with a variable degree of left ventricular hypertrophy which is usually of patchy distribution, and leads to a certain degree of left intraventricular obstruction.

Cardiomegaly↗