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Biomedical subjects

J Bardzik

Publications and source records attributed to J Bardzik.

6 recordsLinked to original sources

Acute silver poisoning through inhalation.

The paper presented a case of acute occupational poisoning with silver vapours. The course of the ailment was very serious. The clinical picture corresponded to the syndrome of the "shock lung"--with extreme respiratory insufficiency. The treatment included administration of steroids, heparin, antibiotics and controlled respiration with a positive endexpiratory pressure (PEEP). The patient was completely cured and fully regained physical fitness. Our observation seems to shake the hitherto predominant view of non-toxicity of metallic silver or its vapours.

Adult↗

Immunoglobulins in persons with long-term exposure to halothane.

In 18 persons (anaesthetists and anaesthetic nurses) with a history of long-term exposure to low concentrations of halothane the activity of aminotransferases, GGTP, and alkaline phosphatase, the bilirubin level and thymol turbidity test were determined and no significant abnormalities were found. On the other hand, determinations of immunoglobulons showed changes in the raised IgM level in 15 out of 18 persons, the difference between the normal level and that found in the present studies being statistically significant. The levels of IgA and IgG were within the normal range. Raised IgM level may be due to stimulation of the immune system by halothane.

Adult↗

Serum enzyme levels in anaesthetic personnel.

The reported studies were carried out on 22 persons, 15 anaesthetists and 7 anaesthetic nurses with a history of long-term exposure to halothane in low concentrations. The activity of gamma-glutamyl-transpeptidase (GGTP) and aminotransferases, the level of bilirubin and thymol turbidity test were determined. No significant abnormalities were found in the mean values of these determinations. In some cases a rise in alkaline phosphatase activity and in two cases a rise of GGTP were found. The results are not suggesting the presence of hepatocellular damage in this group.

Adult↗