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Biomedical subjects

J Bartual

Publications and source records attributed to J Bartual.

17 recordsLinked to original sources
PubMed1982

Twelve years of experience with cytotoxic therapy in malignant tumors of the neck and head.

Since 1968 we have treated with antiblastic drugs 164 malignant tumors recurrent or incurable by surgery or radiotherapy in 151 cases. Different therapeutic methods were employed. Today we have the possibility of selecting alternative options with incipient or relatively delimited carcinomas, principally the substitution of radical surgery by initial associated physical and chemical treatment, so that if there is a cure the consequences of radical surgery can be avoided. We emphasize the curve of two primary cancers of the uvula with 300 mg bleomycin exclusively and the results observed in oropharyngeal and laryngeal carcinomas by using three intermittent Schabel cycles and 4,000 rad Telecobalt, avoiding a radical surgery.

Antineoplastic Agents↗
PubMed1978

Infravestibular horizontal partial laryngectomy. A new surgical method.

We have developed a new functional surgical technique for cancers of the larynx specially those situated glottically and subglottically which are considered remedial to a total laryngectomy. Specifically an infravestibular horizontal partial laryngectomy can be performed to remove neoplasms together with the glottis and subglottis. The larynx then may be reconstructed by suturing the bands to the ascended trachea and the conserved upper half of the tyroid cartilage. The results have been encouraging. Swallowing, phonation and respiration by the natural vias has been obtained in 8 of the 12 patients so operated.

Glottis↗
PubMed1975

Physiological Postrotatory Nystagmus.

Nystagmus elicted by means of rotatory stimuli has been studied in 55 healthy subjects. In each case, 5 different end-velocities have been employed and each postrotatory nystagmus has been quantitatively evaluated by measuring various parameters of its quick phase. The mean values that could be considered as normal were searched for by means of a statistical study, but a great variability in the responses was found. Likewise, the responses of both labyrinths have often been rather asymmetrical. Therefore, such a functional asymmetry of the oculomotor responses, due to a variety of central factors, seems to be a serious diffculty for the practical use of postrotatory nystagmus as a clinical test. The particular meaning of the number of beats is discussed.

Eye Movements↗
PubMedDate not supplied

[The presence of the Epstein-Barr virus in Waldeyer's lymphatic ring during the acute phase of infectious mononucleosis].

The aim of our research was to detect the existence of virus Epstein-Barr genome in the palatine- and the nasopharyngeal tonsil obtained from six patients during the acute phase of the infectious mononucleosis. The presence of EBV-DNA was demonstrated with the help of nucleic acid hybridization techniques (Southern-Blot and in situ hybridization) in the two components of the lymphoepithelial ring of the throat. The pathogenesis and the therapeutic implications of these findings are discussed.

Acute Disease↗
PubMedDate not supplied

[Brain stem auditory evoked potentials in rabbits with hereditary glaucoma associated with hearing loss: morphofunctional correlations].

32 rabbits suffering from simple hereditary glaucoma were studied from the ophthalmological, otological and histopathological point of view. Gonioscopy, tonometry, ophthalmo- and retinography, otoscopy, tympanometry, ABR and the corresponding histopathological studies of the eye and of the cochlea were performed. The simple hereditary glaucoma seems to be causally related with concomitant hearing loss due to congenital endolymphatic hydrops. Further studies are planed.

Acoustic Impedance Tests↗
PubMedDate not supplied

[Presence and distribution of HLA-DR, HLA-DP and HLA-DQ transplant antigens in the human tympanum].

The present morphological study was designed to investigate the expression of HLA class II subregion gene products on human tympanic membrane. Frozen sections from tympanic membrane of 10 cadavers were studied immunohistochemically using monoclonal antibodies. Positive reactions could be detected in the epidermal layer and the subepidermal connective tissue layer of the lamina propia. The implications of our findings on the clinical field of tympanic membrane allografting are discussed.

Histocompatibility Antigens Class II↗
PubMedDate not supplied

[Brainstem auditory evoked potentials (BAEP) in the rabbit. Normal patterns].

Brain stem auditory evoked potentials using skin electrodes have been studied in rabbits. The obtained records are integrated by 6 consecutive waves ranging up to 10 ms. of latency time. The most important, constant and well-performed waves were the I, II and IV waves, which persist until the auditory threshold by 10 dB. The obtained results in 50 ears have been statistically treated. Subsequently, a normal pattern of the BAEP in rabbits has been performed as a base for upcoming papers.

Animals↗
PubMedDate not supplied

[Tuberculosis in current clinical otorhinolaryngology].

39 cases of ENT tuberculosis diagnosed in the last 15 years are studied. We review the annual incidence, the distribution by age and sex and the different found localization: oropharyngeal, laryngeal cervical ganglionar, salivary and otical ones. We analyse the concomitance with tuberculous pulmonary lesions and the results of diagnostic explorations: Mantoux, bacilloscopy and biopsy. We discuss the method, diagnostic difficulties, therapeutic behaviour and the consequences of misdiagnosis.

Adolescent↗
PubMedDate not supplied

[Auditory brain-stem response and electronystagmographic findings in vestibular neuronitis. Neuronitis or neuritis?].

The authors have studied four cases of vestibular neuronitis. General and special ENT exploration were performed and repeated every month. The observation period was three months. ABR and ENG were used for evaluation. The cochlear part of the VIII cranial nerve ist affected without subjective clinical expression. So the patients were diagnosed as having vestibular neuronitis.

Adult↗
PubMedDate not supplied

[Embryonary rhabdomyosarcoma of the middle ear. Apropos of a case].

The subject presented for its rarity is a case of rhabdomyosarcoma embryonal ear in girl patient 6 years old. Her clinic first gave a wrong diagnosis of chronic otitis of the middle ear with otorrhea and facial paralysis. A malignant tumour was suspected during the operation. A histopathology study confirmed the diagnosis of rhabdomyosarcoma. A review of the literature is made and details given of how often it occurs, and incidence, histopathology types, treatment and prognosis.

Child↗
PubMedDate not supplied

Craniocorpography in the diagnosis and therapeutic indication of endolymphatic hydrops.

The glycerol test helps to establish the differential diagnosis between Ménière's disease and other vertigo disturbances, but the test becomes very long and in its primary form informs us only about the cochlear response to the osmotic changes produced by glycerol in the inner ear, and tells us nothing about the vestibular response. In patients with unilateral endolymphatic hydrops we have performed simultaneously the glycerol test with audiometric and craniocorpographic (CCG) control. The response of the vestibular apparatus to the glycerol becomes evident in 84.5% of cases on average in 30 min. By contrast, the variation in the hearing-threshold appears in only 54% of cases and required on average 60 min. At the same time, CCG is easier and shorter to perform than audiometry, showing five different types of response to glycerol. The combined use of audiometry and CCG allows us to predict with sufficient accuracy the response of the endolymphatic hydrops to the treatment, simplifying the therapeutic indication and the choice of the surgical technique.

Adult↗