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Biomedical subjects

J Bellamy

Publications and source records attributed to J Bellamy.

6 recordsLinked to original sources

[Radiation-induced sternal tumors: value of myocutaneous flap of the latissimus dorsi].

Two patients treated by radiotherapy, one 13 years previously for Hodgkin's thymoma and the other 10 years previously for breast cancer, presented with a radiation-induced sternal tumour. The first case had undergone manubriectomy for fibrosarcoma complicated by dehiscence of the skin wound one year prior to referral to our unit: she presented with a haemorrhagic ulcerated recurrence. The lesions were widely excised (skin defect: 13 x 13 cm). The second patient underwent "en bloc" cutaneo-osteomyopericardectomy with omentoplasty onto the pericardium and sternal prosthesis (skin defect: 12 x 7 cm). These tumours are rare, but the radiation-induced skin damage requires wide excision. In both cases, the skin defect was easily repaired by means of a latissimus dorsi myocutaneous flap.

Adult

[Surgery of bronchogenic cancer in aged patients].

The lung cancer mortality rate increases with age, but the progressivity and radioclinical features of this cancer in the elderly are not very different from those observed in younger subjects. As in these subjects, the pretherapeutic evaluation must be complete whenever surgery seems to be possible, but special attention must be paid to the cardiovascular system. Several recent studies have reported postoperative mortality and morbidity rates paradoxically similar, or even lower, in both old and relatively young patients, probably because of a better selection. Moreover, the survival rate at 5 years of the elderly compares favourably with that of younger subjects. Thus, age is not an absolute contra-indication to surgery, but it requires a more rigorous selection and a closer postoperative supervision.

Age Factors

[The resistance to infection of digestive sutures. Experimental study (author's transl)].

The authors study the effects of severe sepsis due to pathogenic gems in large quantity an healing of the suture of the ileum in the rabbit. Contamination of the suture did not lead to any breakdown of the suture whatever the germ. These experimental facts, compared with the data in the literature suggest that the peritoneal serosa ensures efficacious anti-infectious defence, permitting healing of intra-peritoneal digestive sutures in spite of the septic nature of the intestinal contents.

Animals