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J Bharathi Dasan

Publications and source records attributed to J Bharathi Dasan.

6 recordsLinked to original sources
PubMed2004

Reproducibility of regional left ventricular wall thickening obtained by gating resting and redistribution 201Tl myocardial SPECT studies.

BACKGROUND: We have assessed the reproducibility of the estimates of regional left ventricular wall thickening between resting and redistribution Tl gated single photon emission computed tomography (SPECT) studies. METHODS: Thirty patients (28 males, two females) aged between 38 and 72 years (57.0 +/- 8.4 years) underwent resting and redistribution Tl gated SPECT. Perfusion was assessed semi-quantitatively using scores of 0-4. The assessment of wall thickening was performed both visually and by using automated software using scores of 0-3. The assessment of reproducibility was performed in 20 individual segments and 37 pairs of contiguous segments in each patient. RESULTS: In resting studies, mean global left ventricular ejection fraction (LVEF), end diastolic volume and end systolic volume were 34.2 +/- 11.7%, 180.5 +/- 70.6 ml and 123.3 +/- 60.0 ml, respectively. The corresponding values for the redistribution studies were 32.7 +/- 10.1%, 179.7 +/- 70.6 ml and 125.5 + 63.0 ml, respectively. There was good correlation between the resting and redistribution LVEFs (r=0.88), end diastolic volumes (r=0.90) and end systolic volumes (r=0.933). Reproducibility of visual wall thickening was 66% in individual segments and 82% in pairs of contiguous segments, and that of automated wall thickening was 48.0% in individual segments and 68% in pairs of contiguous segments. CONCLUSION: In conclusion, global left ventricular functional parameters obtained by resting Tl gated SPECT studies are highly reproducible in patients with impaired resting left ventricular function and large areas of scarred myocardium. Wall thickening and wall motion data are more reproducible in contiguous segments than in individual segments.

Adult↗
PubMed2003

Scintigraphic patterns of lymphocele in post-renal transplant.

Lymphocele is a common cause of fluid collection in post-renal transplant patients. Most of these patients are routinely followed up with 99mTc diethylenetriaminepentaacetate renal dynamic scintigraphy. The present study retrospectively reviews the range of findings with renal dynamic scintigraphy in documented lymphoceles. A lymphocele was diagnosed when there was a pelvic collection on ultrasonography with a similar biochemical composition to plasma. Four types of scintigraphy patterns were noted in lymphocele in a total of 13 patients. In nine patients there was an initial photopenic area, which progressively filled up with tracer activity equal to that of the background level in delayed images. In two other patients, the activity in the initial photopenic area exceeded the background activity in delayed images. A persistently photopenic area was seen in early and delayed images in the two remaining patients. In addition, a rim of increased tracer activity was noted surrounding the photopenic area in four patients in the early images. In conclusion, an initial photopenic area (with or without a surrounding rim of increased tracer activity), which fills up with tracer in delayed images seems to be the most common pattern seen in lymphoceles in scintigraphic studies of renal transplants. The presence of a rim sign may add confidence to the reporting of a collection as a lymphocele.

Humans↗
PubMed2003

Prevalence of silent gastroesophageal reflux in association with recurrent lower respiratory tract infections.

PURPOSE: Gastroesophageal reflux (GER) has long been associated with pulmonary symptoms and diseases. This retrospective analysis was undertaken to determine the prevalence of GER detected by gastroesophageal scintigraphy in children with recurrent lower respiratory tract infections but none of the typical gastroesophageal symptoms of GER. MATERIALS AND METHODS: A total of 312 children (mean age, 2.36 years; age range, 4 months to 11 years) were evaluated. All studies were performed using Tc-99m sulfur colloid (3.7 to 7.4 MBq; 100 to 200 microCi). RESULTS: Of 312 children, 108 (34.6%) had GER on gastroesophageal scintigraphy. The children were separated into four groups, depending on their age. Group 1 (119 children, younger than 1 year), group 2 (131 children, ages 1 to 3 years), group 3 (36 children, ages 3 to 6 years), and group 4 (26 children, ages 6 to 12 years) showed silent GER with prevalences of 38.7%, 37.4%, 22.2%, and 19.2%, respectively. Because physiologic GER is common in children younger than 18 months, we also analyzed the prevalence of GER in children younger than 18 months and older than 18 months of age. The prevalences of GER in these groups were 41.7% and 24.6%, respectively. CONCLUSIONS: A significant number of children with recurrent lower respiratory tract infection have scintigraphic evidence of GER. This high prevalence, even in children older than 18 months, cannot be ignored. Prospective studies including many patients are needed to establish the exact role of GER in these patients.

Case-Control Studies↗
PubMedDate not supplied

Recurrent osteoid osteoma: a case report with imaging features.

We present a case of a 14-year-old boy, who presented with pain in the left thigh region for 1 year. The pain exacerbated at night, waking up the child and was relieved by salicylates. On the basis of clinical history, conventional radiography, computerized tomography and bone scintigraphy, a diagnosis of osteoid osteoma was made. The tumor was completely excised, and there was complete remission of symptoms. Six months following surgery, the pain recurred in the same region. Conventional radiography revealed dense sclerosis at the surgical site. Three-phase skeletal scintigraphy showed a focal area of increased blood pool activity followed by intense focal uptake in delayed images, characteristic of osteoid osteoma. Computerized tomography confirmed the findings of skeletal scintigraphy.

Adolescent↗
PubMedDate not supplied

Gastroesophageal reflux in asthmatic children not responding to asthma medication: a scintigraphic study in 126 patients with correlation between scintigraphic and clinical findings of reflux.

Gastroesophageal reflux (GER) is frequently found in association with asthma. Successful control of GER in these patients may improve in their asthma symptoms. The present retrospective analysis was undertaken to find out the incidence of GER in asthmatic children not responding to routine antiasthmatic medications and to find out if there is a clinical correlation between the symptoms of GER and scintigraphic evidence of GER in these patients. A total of 126 children with a mean age of 2.31 years and range 6 months to 6 years were evaluated. The children were divided into two groups. Group I (n = 100) consisted of children with asthma but no clinical symptoms of GER. Group II (n = 26) consisted of those children with asthma and clinical symptoms of GER. Radionuclide scintigraphy was performed with 100-200 microCi (3.7-7.4 MBq) of Tc99m-sulphur colloid. All 33 out of 126 (26%) children had GER on scintigraphy. In Group I, only 23 (23%) had reflux while in Group II, 10 (38.5%) had reflux. In conclusion, esophageal scintiscanning can be used to detect GER in asthmatic children refractory to routine antiasthmatic medication irrespective of the presence or absence of symptoms suggestive of GER.

Anti-Asthmatic Agents↗