Biomedical subjects

J Bhattacharjee

Publications and source records attributed to J Bhattacharjee.

5 recordsLinked to original sources

PubMed1992

Epidemiological profile of Japanese encephalitis in Gorakhpur district, Uttar Pradesh, 1982-1988.

An in-depth study of Japanese Encephalitis (JE) situation in Gorakhpur district of Uttar Pradesh from 1982-1988 showed increasing trend in the incidence of JE. Total number of annual cases and case fatality rate (CFR) rose from 118 and 23.7 per cent in 1982 to 772 and 32.2 per cent in 1988 respectively. A definite increase was noticed in the number of cases per block following lull years in 1984 and 1987. Among the total affected 1201 villages, 1083 were affected only once. All age groups were affected and the disease showed marked seasonality during August to November. JE, which came in epidemic form in earlier years has established in the area in endemic form.

Adolescent↗

PubMed1992

Review of the Journal of Communicable Diseases from 1982 through 1991.

Review of medical journals is not common in India. A quantitative review of the articles published in the Journal of Communicable Diseases from 1982 through 1991 was undertaken in the present study to give feedback to all concerned and stimulate them for initiating constructive criticism of medical journals published in India. Articles were categorised as per the classes of four predetermined parameters and variations in the proportions of number of articles under different classes of each parameter are briefly discussed.

Communicable Diseases↗

PubMed1977

Sequential differentiation of retinal cells in the mouse studied by diaphorase staining.

During retinal development in mice the early stages of differentiating of ganglion, amacrine and horizontal cells are characterized by high diaphorase activity in the perikarya. The reaction in the ganglion cells, which start differentiation at day 12 of gestation when the layer of nerve fibres is developing, was first localized near the axonal end, but later, in the period of dendritic growth, it shifted to the scleral side. Amacrine cells were first detected on day 16, and showed a transient activity at the initial stage of their differentiation. A variety of large amacrine cells with long bifurcating processes appeared at day 7 after birth, and showed particularly high TPN diaphorase activity. The horizontal cells could be followed from the 16th day of embryonic life. Their activity increased during the period of formation of the outer plexiform layer. Along the outer limiting membrane diaphorase activity was marked from day 13 of embryonic life, and seemed to concentrate later in the rod inner segments. Activity in the bipolar cells first appeared at day 7 after birth, and increased therafter, coinciding with the period of synaptic development in the outer, plexiform layer. Activity in the Müller cells appeared around 14 days after birth, and was most pronounced in the inner processes and basal end feet. The sequential differentiation of retinal cells and cellular interrelationships during retinal histogenesis are discussed.

Animals↗

PubMed1976

Developmental changes of carbonic anhydrase in the retina of the mouse: a histochemical study.

In the optic cup of early mouse embryos, carbonic anhydrase activity is seen only in the pigment epithelial cells. During the late prenatal period the enzyme appears in the Müller cells, first in the perikarya. During the postnatal development the enzyme activity appears in the radial processes of the Müller cells starting at the vitreal border along with the separation of the outer retinal layers. This is followed by increased activity in the plexiform layers, presumably in the lateral processes. Carbonic anhydrase localization in pigment epithelial and Müller cells attains the adult pattern at about 16 days corresponding with the initiation of retinal function.

Aging↗

PubMed1975

Developmental origin and early differentiation of retinal Müller cells in mice.

During the prenatal development of the retina in mice Müller cells at the initial stage of differentiation show a high level of histochemically detectable non-specific esterase activity. These are the first of the retinal cell types to differentiate and appear at the 11th day of gestation along the vitreal border in the central retina. As development proceeds they appear in more peripheral areas and their perikarya migrate outwardly and become scattered throughout the depth of the retina. Appearance of presumptive Müller cells is followed by rapid growth of the retina and differentiation of the inner retinal layers. With the progress of histogenesis from the central to the peripheral areas the esterase activity in the Müller cells gradually diminishes. The possible significance of early differentiation of Müller cells in promoting growth and histogenesis of retina is discussed.

Animals↗