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Biomedical subjects

J Bienayme

Publications and source records attributed to J Bienayme.

17 recordsLinked to original sources

[Meconium peritonitis. The value of prenatal diagnosis].

Over an eight year period (1980-1987), fifteen cases of meconium peritonitis have been studied. As it has been reported, this pathology is still very rare. Ten pregnancies have been followed on by multiple échographies and the prenatal diagnosis of meconium peritonitis, suspected as early as 24 weeks of amenorrhea, has been established in ten cases. Among these, eight infants have been operated on before twelve hours of life, and for the ninth, surgical treatment was not advocated. The most frequent cause of the pathology is a perforation above a bowel obstruction. Two had cystic fibrosis. Of the 15 infants with meconium peritonitis, nine survived, and among these, one with cystic fibrosis and the one that has not been operated. Prenatal diagnosis in meconium peritonitis is of major interest in taking care early infants that will need an urgent surgical operation in most cases.

Diagnosis, Differential↗

[Congenital diaphragmatic hernia. 120 neonatal cases. Preliminary study].

120 newborns with a congenital diaphragmatic hernia (CDH) were treated during the first day after birth in the Department of Pediatric Surgery at Saint Vincent de Paul's Hospital from 1980 to 1987. The overall survival rate was 40%. The influence of prenatal diagnosis, clinical and anatomical aspects is analysed. The side and the size of the defect, the intra-thoracic liver, the intestinal malrotation and the abdominal hypoplasia are significant prognosis factors. This preliminary study suggests that the natural history of CDH may be responsible of two different diseases: a disease with an early visceral intra-thoracic growth, and a severe lung hypoplasia; another one with a secondary herniation of the intra-abdominal mass, and a better prognosis.

Atrophy↗

[Neonatal gastric perforations].

The authors report 8 cases of primitive neonatal gastric perforation and try to define different etiologies. Mechanisms are varied. According to clinical context, intra-operative macroscopic aspect and histology, vascular, metabolic and mechanical processes are evoked. Each etiological theory is based upon animal experimentation and clinical experience. Actually, different factors are implicated. Latest progress in intensive care has considerably improved prognosis but it is however still serious.

Female↗

[Risk of recurrent laryngeal nerve palsy in surgery of esophageal atresia].

From the last 100 cases of esophageal atresia treated since october 1975, the authors emphasised the incidence of left or right recurrent laryngeal nerve palsy. This incidence is about 20%. Most often, an unilateral palsy is asymptomatic, but in a few cases many complications have been reported. Therefore it is necessary to insist on the surgical and anatomic factors which could increase the risk of a nervous injury and the technics to prevent it.

Esophageal Atresia↗

[Ovarian cysts and tumors in neonates, infants and children (author's transl)].

Twenty-six girls, aged from 0 to 15 years, were operated, upon ovarian cysts and tumors from 1952 to 1977. Before the age of one year, 11 non-neoplastic cysts and 2 benign tumors were observed. After the age of one, 1 non-neoplastic cyst and 12 tumors: 8 germ-cell tumors, 3 tumors of specialized gonadal stroma, and one epithelial tumor. Three germ-cell tumors were malignant (1 girl dead of disease, 2 alive at 2 and 1 1/2 years). All three gonadal stromal tumors are benign (with a follow-up of 3 months, 4 and 20 years). Epidemiology, pathology prognosis and management of these tumors are discussed according the recent literature.

Adolescent↗

[Pseudo-Hirschsprung's disease (author's transl)].

Eight children with pseudo-Hirschsprung's disease are reported. They can be divided into three groups: alimentary ganglioneuromatosis, schwann cell hyperplasia and those with normal appearance by stantard histology. In view of the heterogeneity, histology cannot predict the extent or the prognosis of the disease. Several biopsies at various levels of the alimentary tract and the use of advanced techniques are necessary to assess fully the extent and the type of the lesion and whether it is congenital or acquired. The majority of pseudo-Hirschsprung's disease tend to affect most of alimentary tract, which may lead to the formation of stagnant loops with all their risks. Treatment includes ileostomy, continuous hypoallergenic oral feeding, and manual expression several times a day.

Child↗