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Biomedical subjects

J Bittner

Publications and source records attributed to J Bittner.

At least 19 recordsLinked to original sources
PubMed1992

[The timely diagnosis of postoperative clostridial infection].

Authors report a case of clostridial myonecrosis postcholecystectomy. The causes of the occurrence of this severe, frequently lethal complication are reviewed, as well as the difficulties of an early diagnosis, the only factor able to save the patient. The curative treatment of the detected infection requires the initiation of a series of local and general measures and a permanent cooperation between the surgeon, the specialist in resuscitation and the infectionist.

Acute Disease↗
PubMed1982

Isolation and characterization of a cross-reacting antigen in strains of Bacteroidaceae.

A Bacteroidaceae cross-reacting antigen (BCA) was isolated from several strains belonging to species in the genera Fusobacterium and Bacteroides. We showed that each of the 28 strains examined synthesized either BCA or the O-specific lipopolysaccharide (LPS). The structural difference between the two antigens was demonstrated by passive hemagglutination. BCA coated erythrocytes spontaneously and reacted with equal intensity to all bacterial antisera of BCA+ strains, whereas LPS was species specific and also coated erythrocytes after the antigen was treated with NaOH. BCA is an acid polysaccharide as proven by immunoelectrophoresis and by its capacity to form a salt linkage with lysozyme. Chemical analysis demonstrated the presence of galactosamine, glucosamine, galactose, glucose, mannose, and N-acetyl. BCA was nontoxic and did not contain lipid A in its molecule. The small particle size of BCA determined its hapten character. When attached to acid-treated Salmonella minnesota Re cells, it acted as an immunogen. By immunizing rabbits with this hapten-bacterial cell suspension, we obtained a highly potent antiserum that agglutinated all BCA+ strains.

Antigens, Bacterial↗
PubMed1980

The clinical significance, taxonomy and special methodological problems of the pathogenic clostridia.

The clinical significance of clostridia is much greater than is generally recognized. The organisms are a major cause of septic abortion, Clostridium perfringens being the most important single organism. This species is also the principle agent in food-poisoning. Clostridium botulinum is considered to be one of the main causes of the sudden death syndrome in infants. As clostridia are universally distributed in nature and the human body, the isolation of an organism of this group from the human body is significant only if it can be linked with pathological changes. In the case of histotoxic disease, a direct gramstained smear from the lesion is of paramount importance, since the pathogens are always present in large numbers. Generally, a few simple procedures and tests ensure the rapid isolation and identification of the main pathogenic clostridia. C. perfringens, by far the most important species, may be identified by its ability to produce lecithinase on egg yolk-glucose agar and stormy clot in litmus milk. However, strain identification of this microorganism is much more complicated.

Anaerobiosis↗
PubMed1979

[Reality in the sciences of humans].

The claim of science, which concerns directly human living, to be "objective" and "universal" culminates in the belief, scientific methods could represent reality. Such a science puts men in a couple of scientific laws and suppresses the moment of active doing (accepting or refusing) as a sufficient preassumption of reality. In an alternative way we are looking for a science where reality means invitation to perform own doing.

Human Development↗