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Biomedical subjects

J Bjure

Publications and source records attributed to J Bjure.

At least 37 records · Page 2Linked to original sources
PubMed1984

Long-term follow-up of infants under intensive care with tracheotomy during the period 1956-1965.

Twenty-seven infants who survived intensive care during early infancy in the pioneering period of neonatal intensive care (1956-1965) were investigated after 8-17 years. The selection criterion was maintenance of a tracheotomy for more than 15 days during the first 12 months of life. A variety of clinical, physiological, radiological and psychiatric sequelae was found. Respiratory symptoms were the dominating problem during the post-tracheotomy period. The long-term follow-up revealed that these symptoms had a strong tendency to subside. At the time of the follow-up, as many as 20 children (74%) did not experience any functional impairment.

Child Development↗
PubMed1984

Forced oscillation technique and maximum expiratory flows in bronchial provocation tests in children.

Variables obtained with the forced oscillation technique (total respiratory resistance and impedance at 2, 4 and 12 Hz) and with the forced vital capacity manoeuvre (FVC, FEV1, MMEF, MEF75, MEF50, MEF25) were used in the evaluation of the bronchial allergen challenge test in 2 groups of asthmatic children. Each method was applied in 15 provocation tests and the changes of the different variables, allowing for their respective variations, were compared with the clinical assessment. Agreement with the clinical evaluation was found in 15 of 15 occasions with the forced oscillation technique and in 12 of 15 occasions with the forced vital capacity manoeuvre. With the forced oscillation technique a bronchial reaction was detected in 6 of 10 patients at 1/10 of the allergen concentration that gave positive clinical signs and the single most sensitive variable was resistance determination at 4 Hz, with significant change in 5 of 10 cases. The forced vital capacity manoeuvre allowed detection of a bronchial reaction preceding clinical signs at a tenfold lower allergen concentration in 2 of 9 cases and the most sensitive variables were FEV1 and MEF25.

Adolescent↗
PubMed1983

A case of near-miss SIDS developing an abnormal respiratory reaction to hypoxia.

A SIDS sibling is described who showed a normal respiratory regulation at 1.5 months but who was equipped with an apnea monitor at home on psychological indications. At 3 months he had a near-miss SIDS episode. He was then found to have developed a reaction to hypoxia with appearance of periodic breathing. With theophylline this response pattern was normalized but despite theophylline medication episodes of prolonged apnea occurred.

Apnea↗
PubMed1981

Tracheotomy--a satisfactory method in the treatment of acute epiglottitis. A clinical and functional follow-up study.

A follow-up study, including clinical examination, X-ray and function tests, of 27 children with acute epiglottitis treated with tracheotomy at the ENT-Department, Mölndal Hospital during 1971-1975 has been performed. The function tests were an important part of the investigation and included measurement with the He-dilution technique, flow--volume curves and the forced oscillation technique. No child had any detectable tracheal stenosis or any other serious per- or postoperative complication. The only complication at all was one ugly scar on the neck. The tracheotomized patient needs very little sedation and the time spent at the intensive care unit can be shorter than for those patients treated with nasotracheal intubation.

Acute Disease↗
PubMed1981

Nine years' follow-up of a maximal exercise test in a random population sample of middle-aged men.

A stepwise bicycle exercise test up to maximum was performed in a random population sample of 793 Swedish men, all aged 54 years. High respiratory rate during exercise characterized those who later suffered myocardial infarction (MI) or sudden coronary death (SD). In addition to high cholesterol, high blood pressure (BP), and smoking, low maximal performance, but not ST changes during exercise, increased the risk of MI + SD also in multivariate analysis. Pulse rate, systolic BP at both submaximal and maximal work load were positively correlated with the initial blood pressure level. BP at these work loads was also positively correlated with subsequent BP increase.

Blood Pressure↗
PubMed1980

Autoantibodies to Tamm-Horsfall glycoprotein in children with renal damage associated with urinary tract infections.

Autoantibodies to the Tamm-Horsfall (TH) protein were analyzed in sera from 116 patients with pyelonephritis. The increases in antibody levels were limited in 23 patients with radiological detected renal damage during 31 attacks of acute pyelonephritis. 8 children with abnormally low total and/or unilateral 51Cr EDTA clearance had significantly lower IgG antibody levels to TH protein, than 14 children with normal clearance rate. All 61 children with renal damage had significantly low IgG, IgA and IgM antibody levels to TH protein 6 months after last infection as compared to the reference group. For IgG antibodies, the mean was well below -2 S.D. 12 children with increased serum creatinine had significantly lower IgG antibody levels than those with

Acute Disease↗
PubMed1980

Methodological aspects of renography in children.

Kidney function in children by renography has been evaluated. For reproducible results a high degree of standardization with respect to position, hydration and dosage was necessary. The wide range of kidney size and depth in children requires age-adapted collimators. For practical use for different size have been constructed for the age-groups: less 1 year, 1-5 years, 6-9 years and 10-15 years. A reduction in the surrounding activity of the kidneys is thereby obtained and disturbing influence from the bladder or contralateral kidney is prevented. Kidney function variables from the renogram are presented in terms of uptake and excretion ratios. The correlation between sum of uptake ratios and clearance measurements is good in cases with slight or moderate difference in kidney size. The standardized renographic technique has many advantages for kidney function measurements in children. The method is applicable in all ages, it is simple and reliable without extensive preparations and requires a low radiation dose. Also in children we can confirm the previous opinion obtained in adults that renography is a clinical valuable method of measuring kidney function.

Adolescent↗
PubMed1980

A simple method of background subtraction in two-detector renography.

To increase the accuracy in the routine measurement of the side distribution of kidney function from 131I-Hippuran renograms, a simple method of background subtraction has been developed. Principally a background curve was adapted to the renogram on each side, assuming an initial amplitude corresponding to the amplitude of phase I of the renogram. The amplitudes of the renogram over background after 2 min is recognized as a measured of kidney function and a background quotient was calculated by dividing the background curve amplitude at 2 min with its initial amplitude. Mean values of the background quotient recorder over thorax was 0.62 and over an empty kidney region 0.73. It was found that a quotient of 0.70 could be used generally, thus omitting the need for a background curve registration at each renographic examination.

Adolescent↗
PubMed1980

Evaluation of unilateral kidney function in children. A comparison between renography and separate clearance.

Unilateral kidney function in children was evaluated by determination of 51Cr-EDTA-clearance combined with estimation of side distribution of kidney function by renography. As reference, separate clearance of 51Cr-EDTA, determined by sequential external ureteral occlusions on both sides, was used. A comparison between these two methods was made in 28 patients with varying degrees of unilateral kidney function impairment. A significant correlation was found when the renograms were corrected for extrarenal background activity. Thus, renography in combination with determination of the glomerular filtration rate with 51Cr-EDTA is a valuable method for evaluating separate kidney function in children, both methods being easily performed and requiring small radiation doses.

Adolescent↗
PubMed1980

Kidney split function in children. A comparative study between renography and planimetry from urography.

The suitability of the background-subtracted renogram as a method for separate kidney function in children was evaluated by comparison with planimetry of the individual renal parenchymal area measured from urography. In different groups of renal disorders the total kidney function as reflected by the glomerular filtration rate has been compared with the sum of right and left renal parenchymal areas. The percentage side distribution of kidney function estimated from the renogram combined with measurements of total glomerular filtration rate has been correlated to individual renal parenchymal area. A good correlation was found for both total and separate measurements. A moderate scatter around the regression lines has to be taken into consideration when kidney function is judged from planimetry. A highly significant correlation was observed between renography and planimetry for the percentage distribution of kidney function, indicating that both methods are well suited for determining the side distribution of kidney function. For calculation of individual kidney function, combination of renography and 51Cr-EDTA-clearance offers a reliable method with a modest dose of irradiation.

Adolescent↗
PubMed1980

Nitrogen single breath test, flow-volume curves and spirometry in healthy children, 7-18 years of age.

One hundred and forty school children, 75 boys and 65 girls, aged 7-18 years, underwent the following lung function tests: closing volume, slope of the alveolar plateau, maximal expiratory and inspiratory flows at 75, 50 and 25% of vital capacity, static and dynamic lung volumes. Lung volumes and maximal flows increase with height in an exponential way, the exponents varying between 2.6 and 3.1, while closing volume in per cent of vital capacity and the slope of the alveolar plateau decrease linearily with increasing height. Regression equations are given for each sex with height as determinant.

Adolescent↗
PubMed1979

Peak expiratory flow rate. Reference values for Swedish children.

Reference values for the peak expiratory flow rate assessed by the Wright-McKerrow peak flow meter have been established for Swedish children. The material consisted of 143 boys and 132 girls. We recommend the sexes be considered together. The equation of the regression line is 72.14 x height3 + 96.12. The coefficient of correlation is 0.93 and the residual standard deviation 13.7%.

Body Height↗
PubMed1977

A modified forced oscillation technique for measurements of respiratory resistance.

We present a modification of forced oscillation technique for automated determination of total respiratory resistance during inspiration. The modifications consist of a computerized signal averaging and an optimization technique in the assessment of the resistance value. Thereby a favorable signal-to-noise ratio is obtained, allowing very low superimposed pressure oscillations. The method is validated by comparison with a conventional esophageal balloon method, by estimating added mechanical resistances in healthy subjects and by measuring the effect of bronchodilation in asthmatic children. The coefficient of variation as obtained from day-to-day measurements was about 7%. Mechanical resistances, estimated as the difference in total resistance with and without external resistance, were within 7% of their values determined for the resistances alone. A significant decrease in resistance was obtained in each of the asthmatic children following bronchodilation.

Adolescent↗
PubMed1977

Posterolateral diaphragmatic hernia--long-term results.

During the years 1965--1974, 125 cases of posterolateral diaphragmatic hernia have been operated at five departments of pediatric surgery in Sweden. The overall operative mortality was 50%. A follow-up investigation included 19 cases, where in 12 cases spirometry and in 11 cases studies of the mobility of the diaphragm were included. Physical examination revealed excellent results in most cases. Lung function studies, however, show a moderate (20--30%) reduction, which is not surprising with regard to lung hypoplasia and impaired movement of the diaphragm on the operated side. In adolescence and younger age, these patients are mostly in excellent condition; but later, when lung function is also reduced by the age factor, their neonatal condition may be of importance.

Adolescent↗