PubMed Health⌕ Search

Biomedical subjects

J Bortz

Publications and source records attributed to J Bortz.

9 recordsLinked to original sources

Parental report of sleep problems in children with attentional and learning disorders.

This study examined whether parents of children diagnosed with neurodevelopmental disorders (n = 79) report greater sleep-related problems in their offspring than do parents of normal community-based children (n = 86) on a research questionnaire developed to assess sleep and breathing problems, sleepiness, and behavioral problems. Clinical subgroups included: attention deficit/hyperactivity disorder (ADHD) (n = 43), learning disabilities (LD) (n = 11), and combined ADHD/LD (n = 25). Analyses revealed that parents of children with neurodevelopmental disorders report greater problems along all three dimensions than parents of normal control children. Sleep-related difficulties were reported at the same frequency across all three clinical subgroups. No significant difference between clinical and control groups was noted, however, in the reported length of sleep on weeknights. These preliminary findings suggest that sleep-related problems need to be routinely reviewed as part of the clinical evaluation of neurodevelopmental problems, because they may contribute to and/or exacerbate the behavioral manifestation of these disorders.

Analysis of Variance↗

Immunophenotypic analysis suggests that granuloma faciale is a gamma-interferon-mediated process.

Granuloma faciale (GF) is an uncommon inflammatory dermatosis with characteristic clinical and histologic features. Very little is known about its pathogenesis. We used a battery of immunoperoxidase lymphocyte markers to study the population of hematopoietic cells present in a case of GF. The majority of non-myelocytic hematopoietic cells present were T-helper lymphocytes. The cells stained strongly with antibodies against the interleukin-2 receptor and with anti-lymphocyte functional antigen (LFA 1 alpha) antibodies. Overlying keratinocytes did not stain with ICAM-1 or HLA-DR, which may account for the presence of the Grenz zone in granuloma faciale. These findings suggest that a gamma-interferon-mediated process may play some role in the pathogenesis of this disorder.

Adult↗

Laryngeal incompetence during experimental "relative analgesia" using 50% nitrous oxide in oxygen. A preliminary report.

Ten healthy adult volunteers inhaled 50% nitrous oxide in oxygen while dental treatment was simulated for a period of 30 min. During this time 15 ml of radio-opaque dye was placed at the back of the tongue. A similar control study was performed 1 week later, the subjects inhaling pure oxygen without nitrous oxide. X-ray examination revealed that two of the 10 volunteers had aspirated dye while breathing nitrous oxide and oxygen, but no aspiration was apparent in the control study.

Adolescent↗