Biomedical subjects
Publications and source records attributed to J Brydak-Godowska.
The case of 26-year old male patient with typical clinical intermediate uveitis (vitritis, periphlebitis) with accompanying leucopenia, bradycardia and demyelination focal areas in brain of unknown etiology is presented. The asymptomatic periphlebitis was also found in the eyes of his twin brothers (30 years old) and sister (20 years old).
AIM: Comparison of eye fundus changes in patients in whom malignant hypertension was diagnosed. MATERIAL AND METHODS: 14 patients (6 F, 8 M) aged 24-54 years were examined. In all cases kidney disease was the cause of arterial hypertension. 11 patients underwent kidney transplantation (0.5-20 years before the study), 2 patients was hemodialysed, 1 received only pharmacological treatment. RESULTS: During the first examination in two patients IV grade of hypertensive retinopathy (K-W classification) was found, in the rest of the patients I/II or II grade with typical changes for malignant hypertension in the past (Elschnig's spots) was found. In control examinations (6 months-21 years) the persistence of the previously noticed changes was observed.
We present two patients who developed keratitis sicca and pemphigoid-like symptoms following allogeneic bone marrow transplantation (BMT). The diagnosis of ocular graft-versus-host disease (GvHD) was considerably delayed in both. They were admitted to the reference ophthalmology and posttransplant care departments years after allogeneic BMT, when skin biopsy revealed changes typical for chronic GvHD. In both cases either systemic or local immunosuppressive treatment led to improvement of the clinical condition but did not significantly change patients' quality of life.