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J Brynskov

Publications and source records attributed to J Brynskov.

63 records · Page 4Linked to original sources
PubMed1982

Normal ranges and reproducibility for the quantitative Romberg's test.

Postural stability was measured in 100 healthy people by a quantitative, computer calculated Romberg's test. The persons were aged 20-69 years, and a table of normal ranges is provided. Older men are found to have higher sway figures than young men, while this was not significant in the group of women. In a second part of the study the reproducibility of the method was studied in 10 healthy people. Sway was measured twice a day during 5 consecutive days of work. No significant alterations in the sway measurements were found. The individual variation coefficients ranged from 11-29% (mean value: 18%). By the present study it is concluded that the quantitative Romberg's test is a reasonable way of measuring postural stability.

Humans↗
PubMed1982

Diurnal variations in cobalamin binding plasma proteins.

The diurnal variations in cobalamin-binding plasma proteins were studied in 10 healthy volunteers. The unsaturated cobalamin-binding capacities of transcobalamins (TC-II and R-binders), P-cobalamin and P-protein were measured every third hour during 24h. Only small variations within an interval of +/- 20% were found. Highly significant decrements during the night were a uniform finding. After correction for variations of total plasma protein, the changes became less prominent, but still significant for P-cobalamin and P-R-binders. Hence the mean values of P-R-binders and P-cobalamin were 113 and 533 pmol/1 at 9:00 h, and decreased 12 and 8%, respectively, at 3:00 h. When using cobalamin binding plasma proteins in the monitoring of various malignant, haematological and autoimmune disorders, the specimens should, therefore, be collected at defined hours and in a uniform posture.

Adult↗
PubMed1981

Alcohol and postural imbalance. A force plate study.

A total of 16 normal, medium sized persons were given 20 g of alcohol every hour for 4-5 h. This yielded blood alcohol concentrations between 0.1 mg/ml and 1.7 mg/ml (0.1-1.7%) during the 4-5 h of testing. By use of a computer-assisted force plate system, objective measurements of postural imbalance were performed each hour. An increasing postural imbalance was found at blood alcohol concentrations above 0.6 mg/ml (0.6%). The results illustrate the risk of intake of alcohol by people highly dependent on a safe standing position.

Adult↗
PubMedDate not supplied

Cytokines (immunoinflammatory hormones) and their natural regulation in inflammatory bowel disease (Crohn's disease and ulcerative colitis): a review.

Cytokines, particularly the proinflammatory cytokines, whose role and natural regulation in inflammatory bowel disease are reviewed here, are produced by many cell types, including immune cells. Cytokines function as important hormones of the immune system, and many act both regionally and systemically via specific receptors. The demonstration of increased circulating and mucosal levels of proinflammatory (and other) cytokines (and receptors) in active inflammatory bowel disease does not by itself constitute any proof as to the primary involvement of these mediators. However, they may contribute significantly to disease manifestations, and specific therapeutic intervention at the cytokine or cytokine receptor level may show up to be clinically most relevant. This is underscored by the increasing evidence that proven therapies of inflammatory bowel disease to a great extent seem to function through cytokine modulation.

Animals↗
PubMedDate not supplied

Adhesion molecules in inflammatory and neoplastic intestinal diseases.

Adhesion molecules participate in a broad variety of biological processes, i.e. tumor progression and inflammation, through their involvement in cell-to-cell interactions and immunoinflammatory cell migration. This review describes the basic properties of adhesion molecules with reference to inflammatory bowel disease and colorectal carcinoma. Accumulating data suggest that adhesion molecules could be pathogenetically pertinent to other gastrointestinal disorders such as celiac disease (nontropical sprue) and gastroduodenal ulcer. Future therapeutic approaches in inflammatory and malignant disorders may possibly be development of principles targeting adhesion molecules.

Cell Adhesion Molecules↗