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Biomedical subjects

J Bucy

Publications and source records attributed to J Bucy.

6 recordsLinked to original sources

Refining quality of life: validating a multidimensional factor measure in the severe mentally ill.

Quality of life measurement has historically been characterized by a focus on physical functionality, great variability in definitions and insufficient attention to psychometric properties of measures. The present study examined four core subscales of the Quality of Life Enjoyment Scale (Q-LES-Q) designed to assess subjective quality of life (i.e. physical health, subjective feelings, leisure activities and social relationships) administered to 151 male and female subjects with severe mental illness admitted to a residential community treatment center or a university psychiatric hospital. The use of factor analysis is a common approach to examining construct validity of instruments through the examination of correlated clusters of item responses. Those sets of highly correlated item responses should identify a construct or dimension of related items (i.e. a factor). Two factor approaches, exploratory (i.e. the maximum number of possible factor is unspecified) and restricted (i.e. the maximum number of factors allowed is specified), were employed to examine construct validity of the four Q-LES-Q subscales. In addition, both orthogonal (i.e. independence between factors is maximized) and oblique (i.e. correlated factors are allowed) rotations (arrangements) of factor structure were also investigated to define subscale validity further. Results supported good construct validity for each subscale with either factor approach, i.e. the four proposed subscales were clearly identifiable in the factors (groupings) of correlated item responses from the sample. In both cases, the orthogonal (independent) rotation produced the simplest structure, i.e. the clearest groupings of items. These results indicate that the Q-LES-Q does appear to measure valid dimensions matching those proposed by the subscales and, thus, may be a useful and reliable tool for clinical applications.

Activities of Daily Living↗

Homeless youth: statement of problem and suggested policies.

There are an estimated 100,000 to 300,000 adolescents living on the streets with no supervision, nurturance or regular assistance from a parent or responsible adult. These young people are not "Huck Finns" seeking adventure but have been forced into this lifestyle and frame of mind. The reasons range from family dysfunctions such as abuse, sexual exploitation, neglect, and abandonment to inaction at the "system" level with regard to the overburdened child protective system, inadequate minimum wage, and lack of affordable housing opportunities. The consequences of this national problem are devastating and must be responded to.

Adolescent↗

Heat inactivation of superoxide dismutase in bovine milk.

Superoxide dismutase, and enzyme normal to bovine milk, may be inactivated partially by heat during processing of milk and milk products. A minimal pasteurization temperature (71.7 C for 15 s) does not cause heat inactivation of superoxide dismutase. Higher temperature of pasteurization or systems including a 'vac-heat process' will inactivate a substantial portion of the enzyme. Heat treatments greater than 75 C inactivated more than 20% of the superoxide dismutase. Purified superoxide dismutase fractionated from bovine milk was more sensitive to thermal processing than the superoxide dismutase in bovine milk serum.

Animals↗