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Biomedical subjects

J C Adrian

Publications and source records attributed to J C Adrian.

At least 19 recordsLinked to original sources

Follicular lymphoid hyperplasia of the hard palate: report of a case.

A review of the literature and a case report of follicular lymphoid hyperplasia (FLH) of the hard palate has been presented. This entity should always be considered when confronted with a hard-palate swelling. A diagnosis of FLH generally can be made after a thorough medical and dental examination and immunocytochemical studies of the surgical specimen. Local wide excision of the tumor is suggested as the treatment of choice. During the healing period, the use of a surgical stent will give the patient comfort as the wound heals by secondary intention.

B-Lymphocytes↗

Pulpal response to tricalcium phosphate as a capping agent.

The purpose of this study was to evaluate tricalcium phosphate (TCP) as a pulp-capping agent. Two adult male beagle dogs were used for this investigation. Class I cavities were prepared in the posterior teeth and Class V cavities in the anterior teeth. With the use of a rubber dam and high speed with water coolant, minimal pulp exposures were created in both the experimental and control teeth, by means of a 1/2 round bur. Zinc oxide-eugenol was the temporary filling material used to restore all cavities. In each dog, five teeth served as control and were capped with the use of calcium hydroxide. In one dog, 10 teeth from two quadrants were capped with the tested material (TCP). In the other dog, 11 teeth were capped with TCP. Four teeth from the fourth quadrant in each dog were capped with a mixture of calcium hydroxide and TCP in a ratio of 1:1 by weight (50/50 group.) The two dogs were killed after 70 days. The histologic evaluation of the response to the capping agents and at the exposure site was recorded. A total of 39 teeth were evaluated in this study. It was found that TCP as a capping agent precipitated the highest mean inflammatory response and also demonstrated the highest percentage of reparative dentin formation.

Animals↗

Inverted follicular keratosis of the lip.

Nine cases of inverted follicular keratosis (IFK) of the lips are reported. Eight of these occurred on the lower lip, a previously unreported location. The clinical and histologic features of IFK are discussed. The possibility of confusing this lesion with squamous cell carcinoma is emphasized, and the histologic criteria for differentiation are enumerated.

Adult↗

Ewing's sarcoma of the jaws.

Ewing's sarcoma is an intraosseous malignant tumor of questionable pathogenesis which occurs only occasionally in the jaws. Seventeen cases, eight maxillary and nine mandibular, from the files of the Armed Forces Institute of Pathology (AFIP) are reported. This neoplasm primarily affects children and young adults. Swelling and pain are frequent symptoms. Radiographically, it is most often seen as a destructive, expansile, mottled radiolucent lesion, which may produce a laminated periosteal reaction. The prognosis is poor, although some reports of combined surgery, radiation, and chemotherapy protocols have offered encouragement for increased survival. Histopathologically, Ewing's sarcoma must be differentiated from other small, round-cell malignant neoplasms, such as neuroblastoma and reticulum cell sarcoma.

Adolescent↗

Use of the carbon dioxide laser in sterilization of endodontic reamers.

The object of this study was to test a new method of sterilizing endodontic instruments by using a carbon dioxide laser system. This was done by contaminating endodontic reamers with spores, exposing them to a CO2 laser beam, and checking for their viability by standard microbiologic techniques. It was found that 100 percent of the spores were killed by the CO2 laser. This holds promise as an effective method of sterilizing endodontic instruments in the future.

Bacillus subtilis↗

A new method of sterilization: the carbon dioxide laser.

The use of the carbon dioxide (CO2) laser for sterilization of metal instruments was investigated. Scalpal blades contaminated with bacterial spores were exposed to the laser and subsequently cultured. Our results demonstrate that the CO2 laser effectively sterilizes metal instruments.

Carbon Dioxide↗

Dental pulp reaction to Cavit temporary filling material.

Seventy-two teeth in three Macaque fasicularis monkeys were used to evaluate pulpal response to cavit. Displacement of odontoblastic nuclei was evaluated histologically at three time periods in order to identify initial, early, and final responses. There were no statistically significant differences in pulpal response between Cavit and the zinc oxide-eugenol controls when used in accordance with the manufacturer's directions.

Animals↗

Pulp effects of neodymium laser. A preliminary report.

A total of eight teeth from two rhesus monkeys were exposed to various amounts of neodymium laser radiation. The pulp response was found to be much less severe than that in a study of nineteen teeth previously reported for exposure to similar amounts of ruby laser radiation. If additional studies support this initial finding, it is suggested that a re-evaluation of neodymium laser-mediated procedures in vital teeth be initiated.

Animals↗

The effect of topical antihistamine on the initial pulpal inflammatory response of monkey teeth.

Cavity preparations were made in sixty sound teeth of healthy monkeys. Thermal trauma was delivered to the pulps of all teeth through application of a heated soldering iron to the floor of a cavity preparation. Fifteen teeth were randomly designated as controls and were restored immediately with zinc oxide and eugenol. Forty-five teeth were designated as test teeth. These were treated topically with a 4 per cent antihistamine solution and restored with zinc oxide and eugenol. Histologic sections were prepared to show the effect of the antihistamine on the thermally initiated inflammatory response during the postoperative period. No significant difference was observed in the inflammatory reactions of treated or untreated pulps. A 4 per cent aqueous solution of topically applied antihistamine did not appear to be of any significant value in obviating pulpal inflammation.

Animals↗